Events

Date: 4 March 2026   Time: 13:00 - 14:00

Location: MB-503

Polymer translocation through narrow pores is a fundamental process with broad relevance, ranging from biological phenomena such as DNA transport through nuclear pores to the development of nanopore-based sequencing technologies. In this work, we investigate the stochastic dynamics of polymer translocation using a combination of exact enumeration techniques and coarse-grained molecular dynamics simulations. The exact enumeration provides detailed insights into the entropic landscape and partition functions associated with different translocation states, while the simulation results capture the dynamic aspects of driven and unbiased translocation. We analyze translocation time distributions, scaling behaviors, and the influence of parameters such as polymer length, driving force, and pore-polymer interaction. Our results reveal distinct dynamical regimes and highlight the critical role of fluctuations and configurational entropy in governing the translocation process. These findings contribute to a deeper theoretical understanding and provide a framework for interpreting and guiding experimental studies in both synthetic and biological contexts.