Welcome to The Centre for Molecular Cell Biology
Our researchers study the biological organisation of cells, and the molecular mechanisms underpinning their function in health, disease and sustainable living. Our wide angle of exploration spans from the atomic structures and dynamics of living systems to their organisation in sub-cellular assemblies, cells, tissues, and organs. We are keen to translate of our fundamental discoveries into the drug discovery process, into clinical advances, and into the biotechnology industry. We commonly adopt an interdisciplinary approach including advanced imaging and genetic engineering techniques. This is frequently combined with high performance computing powered by artificial intelligence and machine learning. Collaboratively we address the grand challenges of food security, healthy ageing, anti-microbial resistance, green energy, and sustainable living.
Events
Mon 24 - Tue 25 Jun 2024 | Bacterial Machines in Action Centre for Molecular Cell Biology |
Recent Publications
- Peripolli S, Meneguello L, Perrod C, Singh T, Patel H, Rahman ST, Kiso K, Thorpe P, Calvanese V, Bertoli C and de Bruin RAM (2024). Oncogenic c-Myc induces replication stress by increasing cohesins chromatin occupancy in a CTCF-dependent manner. Nature Communications, Springer Nature vol. 15 (1)
21-02-2024 - Tian Y, Shang Q, Liang R and Viles JH (2024). Copper(II) Can Kinetically Trap Arctic and Italian Amyloid‑β40 as Toxic Oligomers, Mimicking Cu(II) Binding to Wild-Type Amyloid‑β42: Implications for Familial Alzheimer’s Disease. JACS Au, American Chemical Society (ACS)
06-02-2024 - Khursheed A and Viles JH (2024). Impact of Membrane Phospholipids and Exosomes on the Kinetics of Amyloid-β Fibril Assembly. Journal of Molecular Biology, Elsevier vol. 436 (6)
03-02-2024