Prof Conrad Bessant

Conrad Bessant

Professor of Bioinformatics

School of Biological and Behavioural Sciences
Queen Mary University of London
ORCID Google Scholar LinkedIn

Research

data science, computational biology, bioinformatics, artificial intelligence, drug discovery

Interests

Conrad Bessant has ~25 years’ experience of data science, tackling research questions in analytical chemistry, biomolecular science, and qualitative healthcare studies.

His overarching research interest is the automation of scientific discovery in the biomedical domain. While some aspects of biomedical research such as data acquisition and routine analysis are already commonly automated, fundamental research activities such as hypothesis generation, identification of relevant datasets and interpretation of results still require extensive input from human experts. This is becoming increasingly intractable as available datasets grow in size and complexity – innovative solutions to automate the process are needed.

Technologies being used by Conrad’s research group to automate the scientific discovery process include machine learning, relational modelling, network science and Bayesian inference.

Conrad is based in QMUL’s Digital Environment Research Institute. He leads QMUL’s MSc Bioinformatics programme and is the academic lead of the UKRI AI for Drug Discovery Doctoral Training Programme.

Publications

solid heart iconPublications of specific relevance to the Centre for Molecular Cell Biology

2023

bullet iconBranson N, Cutillas PR and Bessant C (2023). Comparison of multiple modalities for drug response prediction with learning curves using neural networks and XGBoost. Bioinformatics Advances, Oxford University Press (OUP) vol. 4 (1) 
23-12-2023
bullet iconSaihi H, Bessant C and Alazawi W (2023). Automated and reproducible cell identification in mass cytometry using neural networks. Briefings in Bioinformatics, Oxford University Press 
02-11-2023
bullet iconElder GA and Bessant C (2023). Inferring Compensatory Kinase Networks in Yeast using Prolog. Electronic Proceedings in Theoretical Computer Science, Open Publishing Association vol. 385, 260-273.  
12-09-2023
bullet iconDe Los Angeles Colomina Basanta C, Bazzi M, Hijazi M, Bessant C and Cutillas PR (2023). Community detection in empirical kinase networks identifies new potential members of signalling pathways. PLOS Computational Biology, Public Library of Science (PLoS) vol. 19 (6) 
23-06-2023
bullet iconBessant C, Abdollahyan M and Smeraldi F (2023). CO51 Understanding the Lived Experience of Patients By Mining Online Health Boards. Value in Health, Elsevier vol. 26 (6), s23-s24.  
01-06-2023
bullet iconByrom B, Bessant C, Smeraldi F, Abdollahyan M, Bridges Y, Chowdhury M and Tahsin A (2023). Deriving Meaningful Aspects of Health Related to Physical Activity in Chronic Disease: Concept Elicitation Using Machine Learning–Assisted Coding of Online Patient Conversations. Value in Health, Elsevier vol. 26 (7), 1057-1066.  
16-02-2023

2022

bullet iconBessant C, Bridges Y, Chowdhury M, Tahsin A, Abdollahyan M, Smeraldi F and Byrom B (2022). PCR3 Assessing Concept Saturation and Sample Representativeness When Using Social Media Data to Inform Concept Elicitation Studies. Value in Health, Elsevier vol. 25 (12) 
01-12-2022
bullet iconWaller KJ, Saihi H, Li W, Brindley JH, De Jong A, Syn W-K, Bessant C and Alazawi W (2022). Single-cell phenotypes of peripheral blood immune cells in early and late stages of non-alcoholic fatty liver disease. Clinical and Molecular Hepatology, The Korean Association for the Study of the Liver vol. 29 (2), 417-432.  
21-11-2022
bullet iconBridges Y, Chowdhury M, Tahsin A, Bessant C, Abdollahyan M, Smeraldi F and Byrom B (2022). POSB338 Identification of Meaningful Aspects of Physical Activity: Concept Elicitation By AI-Assisted Coding of Online Patient Conversations. Value in Health, Elsevier vol. 25 (1) 
01-01-2022

2021

bullet iconPatel R, Smeraldi F, Abdollahyan M, Irving J and Bessant C (2021). Analysis of mental and physical disorders associated with COVID-19 in online health forums: a natural language processing study. BMJ Open, BMJ vol. 11 (11) 
01-11-2021

2020

bullet iconGomez EA, Colas RA, Souza PR, Hands R, Lewis MJ, Bessant C, Pitzalis C and Dalli J (2020). Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis. Nature Communications, Springer Nature vol. 11 (1) 
27-10-2020
bullet iconGadaleta E, Fourgoux P, Pirró S, Thorn GJ, Nelan R, Ironside A, Rajeeve V, Cutillas PR, Lobley AE, Wang J, Gea E, Ross-Adams H, Bessant C, Lemoine NR, Jones LJ and Chelala C (2020). Characterization of four subtypes in morphologically normal tissue excised proximal and distal to breast cancer. npj Breast Cancer, Nature Research (part of Springer Nature) vol. 6 (1) 
21-08-2020
bullet iconGadaleta E, Fourgoux P, Pirró S, Thorn GJ, Nelan R, Ironside A, Rajeeve V, Cutillas PR, Lobley AE, Wang J, Gea E, Ross-Adams H, Bessant C, Lemoine NR, Jones LJ and Chelala C (2020). Characterization of four subtypes in morphologically normal tissue excised proximal and distal to breast cancer. NPJ Breast Cancer vol. 6 (1) 
21-08-2020
bullet iconHijazi M, Smith R, Rajeeve V, Bessant C and Cutillas PR (2020). Reconstructing kinase network topologies from phosphoproteomics data reveals cancer-associated rewiring. Nature Biotechnology, Nature Research 
20-01-2020
bullet iconAbdollahyan M, Smeraldi F, Patel R and Bessant C (2020). Investigating Comorbidity of Mental and Physical Disorders in Online Health Forums. Proceedings of the 3rd International Conference on Applications of Intelligent Systems
07-01-2020

2019

bullet iconCutillas PR, Hijazi M, Smith R, Bessant C and Britton D (2019). Abstract C088: Chemical phosphoproteomics systematically identifies circuitries of kinase networks in cancer cells and predicts their response to kinase inhibitors. 
01-12-2019

2018

bullet iconRuiz-Romero C, Picchi F, Fernández-Puente P, González-Rodríguez L, Hands R, Calamia V, Camacho-Encina M, Bessant C, Pitzalis C and Blanco FJ (2018). THU0052 A circulating protein signature correlates with synovial pathotypes in rheumatoid arthritis patients. THURSDAY, 14 JUNE 2018
01-06-2018
bullet iconRuiz-Romero C, Picchi F, González-Rodríguez L, Fernández-Puente P, Hands R, Calamia V, Camacho-Encina M, Bessant C, Pitzalis C and Blanco FJ (2018). SAT0074 Identification of a protein panel useful for the prediction of response to methotrexate in rheumatoid arthritis patients. Saturday, 16 JUNE 2018
01-06-2018
bullet iconSaha S, Matthews DA and Bessant C (2018). High throughput discovery of protein variants using proteomics informed by transcriptomics. Nucleic Acids Research, Oxford University Press (OUP) vol. 46 (10) 
30-04-2018
bullet iconAbdollahyan M, Mondragón RJ, Bessant C and Smeraldi F (2018). Visualising the topological structure of health-elated message board user networks. 
01-01-2018
bullet iconRuiz-Romero C, Picchi F, Fernandez P, Gonzalez L, Hands R, Calamia V, Camacho M, Bessant C, Pitzalis C and Blanco FJ (2018). Identification of a Panel of Circulating Proteins Associated to Synovial Pathotypes in Early Rheumatoid Arthritis Patients. 
01-01-2018
bullet iconRuiz-Romero C, Picchi F, Gonzalez L, Hands R, Calamia V, Fernandez P, Camacho M, Paz R, Bessant C, Pitzalis C and Blanco FJ (2018). Identification of a Protein Profile Useful to Predict Response to Methotrexate in Early Rheumatoid Arthritis Patients. 
01-01-2018

2017

bullet iconPearce OMT, Delaine-Smith R, Maniati E, Nichols S, Wang J, Böhm S, Rajeeve V, Ullah D, Chakravarty P, Jones RR, Montfort A, Dowe T, Gribben J, Jones JL, Kocher HM, Serody JS, Vincent BG, Connelly J, Brenton JD, Chelala C, et al. (2017). Deconstruction of a metastatic tumor microenvironment reveals a common matrix response in human cancers. Cancer Discov 
01-12-2017
bullet iconSAHA S, Chatzimichali E, Matthews D and Bessant C (2017). PITDB: a database of translated genomic elements. Nucleic Acids Research, Oxford University Press 
09-10-2017
bullet iconBalkwill FR, Pearce OM, Delaine-Smith R, Maniati E, Nichols S, Wang J, Bessant C and Knight M (2017). Abstract 5558: Deconstruction of a human tumor microenvironment. 
01-07-2017
bullet iconMaringer K, Yousuf A, Heesom KJ, Fan J, Lee D, Fernandez-Sesma A, Bessant C, Matthews DA and Davidson AD (2017). Proteomics informed by transcriptomics for characterising active transposable elements and genome annotation in Aedes aegypti. BMC Genomics vol. 18 (1), 101-101.  
19-01-2017
bullet iconBessant C (2017). Acknowledgements. New Developments in Mass Spectrometry vol. 2017-January (5) 
01-01-2017

2016

bullet iconSaha S, Matthews D and Bessant C (2016). Chapter 16 Proteomics Informed by Transcriptomics. Proteome Informatics  385-405.  
15-11-2016
bullet iconBessant C (2016). Chapter 1 Introduction to Proteome Informatics. Proteome Informatics  1-14.  
15-11-2016
bullet icon (2016). Proteome Informatics., Editors: Bessant C. 
15-11-2016
bullet iconWalton C, Montoya MPB, Fowler DP, Turner C, Jia W, Whitehead RN, Griffiths L, Waring RH, Ramsden DB, Cole JA, Cauchi M, Bessant C, Naylor SJ and Hunter JO (2016). Enteral feeding reduces metabolic activity of the intestinal microbiome in Crohn’s disease: an observational study. European Journal of Clinical Nutrition, Nature Publishing Group: Open Access Hybrid Model Option B vol. 70, 1052-1056.  
11-05-2016
bullet iconCauchi M, Weber CM, Bolt BJ, Spratt PB, Bessant C, Turner DC, Willis CM, Britton LE, Turner C and Morgan G (2016). Evaluation of gas chromatography mass spectrometry and pattern recognition for the identification of bladder cancer from urine headspace. Analytical Methods, Royal Society of Chemistry (RSC) vol. 8 (20), 4037-4046.  
01-01-2016
bullet iconMohareb F, Papadopoulou O, Panagou E, Nychas G-J and Bessant C (2016). Ensemble-based support vector machine classifiers as an efficient tool for quality assessment of beef fillets from electronic nose data. Analytical Methods, Royal Society of Chemistry (RSC) vol. 8 (18), 3711-3721.  
01-01-2016

2015

bullet iconChatzimichali EA and Bessant C (2015). Novel application of heuristic optimisation enables the creation and thorough evaluation of robust support vector machine ensembles for machine learning applications. Metabolomics, Springer Nature vol. 12 (1) 
21-11-2015
bullet iconQi D, Zhang H, Fan J, Perkins S, Pisconti A, Simpson DM, Bessant C, Hubbard S and Jones AR (2015). The mzqLibrary - An open source Java library supporting the HUPO-PSI quantitative proteomics standard. Proteomics vol. 15 (18), 3152-3162.  
01-09-2015
bullet iconFan J, Saha S, Barker G, Heesom KJ, Ghali F, Jones AR, Matthews DA and Bessant C (2015). Galaxy Integrated Omics: Web-based Standards-Compliant Workflows for Proteomics Informed by Transcriptomics*[S]. Molecular & Cellular Proteomics, Elsevier vol. 14 (11), 3087-3093.  
12-08-2015
bullet iconQi D, Zhang H, Fan J, Perkins S, Pisconti A, Simpson DM, Bessant C, Hubbard S and Jones AR (2015). The mzqLibrary – An open source Java library supporting the HUPO‐PSI quantitative proteomics standard. Proteomics, Wiley vol. 15 (18), 3152-3162.  
14-07-2015
bullet iconCauchi M, Fowler DP, Walton C, Turner C, Waring RH, Ramsden DB, Hunter JO, Teale P, Cole JA and Bessant C (2015). Comparison of GC-MS, HPLC-MS and SIFT-MS in conjunction with multivariate classification for the diagnosis of Crohn's disease in urine. Analytical Methods, Royal Society of Chemistry (RSC) vol. 7 (19), 8379-8385.  
01-01-2015

2014

bullet iconGonzalez-Galarza FF, Qi D, Fan J, Bessant C and Jones AR (2014). A tutorial for software development in quantitative proteomics using PSI standard formats. Biochim Biophys Acta vol. 1844 (1 Pt A), 88-97.  
01-01-2014
bullet iconBessant C, Oakley D and Shadforth I (2014). Building Bioinformatics Solutions. 
01-01-2014
bullet iconSattlecker M, Stone N and Bessant C (2014). Current trends in machine-learning methods applied to spectroscopic cancer diagnosis. TrAC Trends in Analytical Chemistry, Elsevier/Science Direct vol. 59, 17-25.  
01-01-2014
bullet iconCauchi M, Fowler DP, Walton C, Turner C, Jia W, Whitehead RN, Griffiths L, Dawson C, Bai H, Waring RH and others (2014). Application of gas chromatography mass spectrometry (GC–MS) in conjunction with multivariate classification for the diagnosis of gastrointestinal diseases. Metabolomics, Springer US vol. 10 (6), 1113-1120.  
01-01-2014
bullet iconBessant C, Oakley D and Shadforth I (2014). Building Bioinformatics Solutions 2nd Edition. 
01-01-2014
bullet iconGonzalez-Galarza FF, Qi D, Fan J, Bessant C and Jones AR (2014). A tutorial for software development in quantitative proteomics using PSI standard formats. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS vol. 1844 (1), 88-97.  
01-01-2014

2013

bullet iconWalton C, Fowler DP, Turner C, Jia W, Whitehead RN, Griffiths L, Dawson C, Waring RH, Ramsden DB, Cole JA, Cauchi M, Bessant C and Hunter JO (2013). Analysis of volatile organic compounds of bacterial origin in chronic gastrointestinal diseases. Inflamm Bowel Dis vol. 19 (10), 2069-2078.  
01-09-2013
bullet iconWalzer M, Qi D, Mayer G, Uszkoreit J, Eisenacher M, Sachsenberg T, Gonzalez-Galarza FF, Fan J, Bessant C, Deutsch EW, Reisinger F, Vizcaíno JA, Medina-Aunon JA, Albar JP, Kohlbacher O and Jones AR (2013). The mzQuantML data standard for mass spectrometry-based quantitative studies in proteomics. Mol Cell Proteomics vol. 12 (8), 2332-2340.  
01-08-2013
bullet iconBessant C and Fan J (2013). Computational approaches to selected reaction monitoring assay design. Methods Mol Biol vol. 1007, 219-235.  
01-01-2013
bullet iconBessant C and Fan J (2013). Computational approaches to selected reaction monitoring assay design. Methods in Molecular Biology vol. 1007, 219-235.  
01-01-2013

2012

bullet iconEvans VC, Barker G, Heesom KJ, Fan J, Bessant C and Matthews DA (2012). De novo derivation of proteomes from transcriptomes for transcript and protein identification. Nat Methods vol. 9 (12), 1207-1211.  
01-12-2012
bullet iconGonzalez-Galarza FF, Lawless C, Hubbard SJ, Fan J, Bessant C, Hermjakob H and Jones AR (2012). A critical appraisal of techniques, software packages, and standards for quantitative proteomic analysis. OMICS vol. 16 (9), 431-442.  
01-09-2012
bullet iconFan J, Mohareb F, Bond NJ, Lilley KS and Bessant C (2012). MRMaid 2.0: mining PRIDE for evidence-based SRM transitions. OMICS vol. 16 (9), 483-488.  
01-09-2012
bullet iconJia W, Whitehead RN, Griffiths L, Dawson C, Bai H, Waring RH, Ramsden DB, Hunter JO, Cauchi M, Bessant C, Fowler DP, Walton C, Turner C and Cole JA (2012). Diversity and distribution of sulphate-reducing bacteria in human faeces from healthy subjects and patients with inflammatory bowel disease. FEMS Immunol Med Microbiol vol. 65 (1), 55-68.  
01-06-2012
bullet iconIkeno S, Sano K, Cauchi M, Takatsuji Y, Bessant C and Haruyama T (2012). Colorimetric analysis of agonistic/antagonistic actions on estrogen receptor using peptide-functionalized gold nanoparticle sensor. 
17-05-2012
bullet iconFan J, Mohareb F, Jones AME and Bessant C (2012). MRMaid: The SRM Assay Design Tool for Arabidopsis and Other Species. Front Plant Sci vol. 3 
01-01-2012

2011

bullet iconThiollet S, Bessant C and Morgan SL (2011). Application of multiple response optimization design to quantum dot-encoded microsphere bioconjugates hybridization assay. Anal Biochem vol. 414 (1), 23-30.  
01-07-2011
bullet iconPanagou EZ, Mohareb FR, Argyri AA, Bessant CM and Nychas G-JE (2011). A comparison of artificial neural networks and partial least squares modelling for the rapid detection of the microbial spoilage of beef fillets based on Fourier transform infrared spectral fingerprints. Food Microbiol vol. 28 (4), 782-790.  
01-06-2011
bullet iconWeber CM, Cauchi M, Patel M, Bessant C, Turner C, Britton LE and Willis CM (2011). Evaluation of a gas sensor array and pattern recognition for the identification of bladder cancer from urine headspace. Analyst vol. 136 (2), 359-364.  
21-01-2011
bullet iconJohnson PE, Baumgartner S, Aldick T, Bessant C, Giosafatto V, Heick J, Mamone G, O'Connor G, Poms R, Popping B, Reuter A, Ulberth F, Watson A, Monaci L and Mills ENC (2011). Current perspectives and recommendations for the development of mass spectrometry methods for the determination of allergens in foods. J AOAC Int vol. 94 (4), 1026-1033.  
01-01-2011
bullet iconCauchi M, Bianco L and Bessant C (2011). The quantification of pollutants in drinking water by use of artificial neural networks. Nat. Comput. vol. 10, 77-90.  
01-01-2011
bullet iconSattlecker M, Baker R, Stone N and Bessant C (2011). Support vector machine ensembles for breast cancer type prediction from mid-FTIR micro-calcification spectra. Chemometrics and Intelligent Laboratory Systems, Elsevier vol. 107, 363-370.  
01-01-2011
bullet iconSattlecker M, Stone N, Smith J and Bessant C (2011). Assessment of robustness and transferability of classification models built for cancer diagnostics using Raman spectroscopy. Journal of Raman Spectroscopy, Wiley Online Library vol. 42, 897-903.  
01-01-2011
bullet iconBessant C (2011). Data Mining for Genomics and Proteomics: Analysis of Gene and Protein Expression Data Darius M. Dziuda John Wiley and Sons, 2010, p. 327 ISBN: 978-0-470-16373-3. Proteomics, WILEY-VCH Verlag vol. 11, 3768-3768.  
01-01-2011
bullet iconBessant C (2011). Experiences in Pattern Recognition for Machine Olfaction. 
01-01-2011

2010

bullet iconKolk A, Hoelscher M, Maboko L, Jung J, Kuijper S, Cauchi M, Bessant C, van Beers S, Dutta R, Gibson T and Reither K (2010). Electronic-nose technology using sputum samples in diagnosis of patients with tuberculosis. J Clin Microbiol vol. 48 (11), 4235-4238.  
01-11-2010
bullet iconSattlecker M, Bessant C, Smith J and Stone N (2010). Investigation of support vector machines and Raman spectroscopy for lymph node diagnostics. Analyst vol. 135 (5), 895-901.  
01-05-2010
bullet iconCham Mead JA, Bianco L and Bessant C (2010). Free computational resources for designing selected reaction monitoring transitions. Proteomics vol. 10 (6), 1106-1126.  
01-03-2010
bullet iconPagliarini R, Bianco L, Manca V and Bessant C (2010). Linking Bistable Dynamics to Metabolic P Systems. Eighth Brainstorming Week on Membrane Computing Universidad de Sevilla, Seville, Spain 1 Feb 2010 - 5 Feb 2010
05-02-2010
bullet iconChem Mead JA, Bianco L and Bessant C (2010). Mining proteomic MS/MS data for MRM transitions. Methods Mol Biol vol. 604, 187-199.  
01-01-2010
bullet iconCham JA, Bianco L, Barton C and Bessant C (2010). MRMaid-DB: a repository of published SRM transitions. J Proteome Res vol. 9 (1), 620-625.  
01-01-2010
bullet iconTetsuya H (2010). Discerning data analysis methods to clarify agonistic/antagonistic actions on the ion flux assay of ligand-gated ionotropic glutamate receptor on engineered post-synapse model cells. Journal of Biosensors & Bioelectronics 
01-01-2010
bullet iconTanoue C, Asakawa H, Cauchi M, Bessant C, Ikeno S and Haruyama T (2010). Tissular model/sensor seamless system for qualified analysis and its characterization. Biochemical Engineering Journal, Elsevier vol. 52, 110-115.  
01-01-2010
bullet iconKolk A, Hoelscher M, Maboko L, Jung J, Kuijper S, Cauchi M, Bessant C, van Beers S, Dutta R, Gibson T and others (2010). Electronic-nose technology in diagnosis of TB patients using sputum samples. Journal of Clinical Microbiology, Am Soc Microbiol 
01-01-2010
bullet iconJia W, Griffiths L, Whitehead B, Basser SJ, Dawson C, Turner C, Bessant C, Fowler D, Walton C, Ramsden D and others (2010). ABUNDANCE OF SULPHATE REDUCING BACTERIA IN INFLAMMATORY BOWEL DISEASE. 
01-01-2010

2009

bullet iconSpooner AD, Bessant C, Turner C, Knobloch H and Chambers M (2009). Evaluation of a combination of SIFT-MS and multivariate data analysis for the diagnosis of Mycobacterium bovis in wild badgers. Analyst vol. 134 (9), 1922-1927.  
01-09-2009
bullet iconBlanco L, Mead JA and Bessant C (2009). Comparison of novel decoy database designs for optimizing protein identification searches using ABRF sPRG2006 standard MS/MS data sets. J Proteome Res vol. 8 (4), 1782-1791.  
01-04-2009
bullet iconBabrah J, McCarthy K, Lush RJ, Rye AD, Bessant C and Stone N (2009). Fourier transform infrared spectroscopic studies of T-cell lymphoma, B-cell lymphoid and myeloid leukaemia cell lines. Analyst vol. 134 (4), 763-768.  
01-04-2009
bullet iconMead JA, Bianco L, Ottone V, Barton C, Kay RG, Lilley KS, Bond NJ and Bessant C (2009). MRMaid, the web-based tool for designing multiple reaction monitoring (MRM) transitions. Mol Cell Proteomics vol. 8 (4), 696-705.  
01-04-2009
bullet iconMoczko E, Meglinski IV, Bessant C and Piletsky SA (2009). Dyes assay for measuring physicochemical parameters. Anal Chem vol. 81 (6), 2311-2316.  
15-03-2009
bullet iconMead JA, Bianco L and Bessant C (2009). Recent developments in public proteomic MS repositories and pipelines. Proteomics vol. 9 (4), 861-881.  
01-02-2009
bullet iconMonteiro MB, Pintado ME, Malcata FX, Bessant C and Moreira PR (2009). Development of a Workflow for Protein Sequence Analysis Based on the Taverna Workbench Software., Editors: Omatu S, Rocha M, Bravo J, Riverola FF, Corchado E, Bustillo A and Corchado JM. 
01-01-2009
bullet iconThanaraj T, Terry LA and Bessant C (2009). Chemometric profiling of pre-climacteric Sri Lankan mango fruit (< i> Mangifera indica L.). Food Chemistry, Elsevier vol. 112, 786-794.  
01-01-2009
bullet iconTottey S, Robinson N, Waldron K, Firbank S and Bessant C (2009). Protein folding location determines binding of manganese versus copper. Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, Pergamon vol. 153, S159-S159.  
01-01-2009

2008

bullet iconRobinson N, Waldron K, Tottey S and Bessant C (2008). Metalloprotein metal pools: identification and quantification by coupling native and non-native separations through principal component analysis. Protocol Exchange, Springer Nature 
12-11-2008
bullet iconTottey S, Waldron KJ, Firbank SJ, Reale B, Bessant C, Sato K, Cheek TR, Gray J, Banfield MJ, Dennison C and Robinson NJ (2008). Protein-folding location can regulate manganese-binding versus copper- or zinc-binding. Nature vol. 455 (7216), 1138-1142.  
23-10-2008
bullet iconStott W, Ryan A, Jacobs IJ, Menon U, Bessant C and Jones C (2008). OSPACS: Ultrasound image management system. Source Code Biol Med vol. 3 
20-06-2008
bullet iconCauchi M, Bessant C and Setford S (2008). Simultaneous Quantitative Determination of Cadmium, Lead, and Copper on Carbon-Ink Screen-Printed Electrodes by Differential Pulse Anodic Stripping Voltammetry and Partial Least Squares Regression. Electroanalysis, Wiley Online Library vol. 20, 2571-2577.  
01-01-2008
bullet iconMead J, Bianco L and Bessant C (2008). Using Bioinformatics to Increase Speed and Reduce Uncertainty in Protein Biomarker Discovery. Cranfield Multi-Strand Conference: Creating Wealth Through Research and Innovation vol. 6, 118-118.  
01-01-2008

2007

bullet iconMead JA, Shadforth IP and Bessant C (2007). Public proteomic MS repositories and pipelines: available tools and biological applications. Proteomics vol. 7 (16), 2769-2786.  
01-08-2007
bullet iconBabrah J, McCarthy KP, Lush R, Rye AD, Bessant C and Stone N (2007). FT-infrared spectroscopic studies of lymphoma, lymphoid, and myeloid leukemia cell lines. Diagnostic Optical Spectroscopy in Biomedicine IV
05-07-2007
bullet iconKumuthini J, Jouffe L and Bessant C (2007). A Novel Graph Optimisation Algorithm for the Extraction of Gene Regulatory Networks from Temporal Microarray Data., Editors: Hochreiter S and Wagner R. 
01-01-2007
bullet iconGoodacre R, Broadhurst D, Smilde AK, Kristal BS, Baker JD, Beger R, Bessant C, Connor S, Capuani G, Craig A and others (2007). Proposed minimum reporting standards for data analysis in metabolomics. Metabolomics, Springer US vol. 3, 231-241.  
01-01-2007
bullet iconBessant C (2007). Microarray Analysis Software and its Applications. Handbook of Biosensors and Biochips, John Wiley & Sons, Ltd 
01-01-2007
bullet iconBabrah J, McCarthy KP, Lush R, Rye AD, Bessant C and Stone N (2007). FT-infrared spectroscopic studies of lymphoma, lymphoid, and myeloid leukemia cell lines [6628-28]. PROCEEDINGS-SPIE THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING, International Society for Optical Engineering; 1999 vol. 6628, 6628-6628.  
01-01-2007
bullet iconBabrah J, McCarthy KP, Lush R, Rye AD, Bessant C and Stone N (2007). FT-infrared spectroscopic studies of lymphoma, lymphoid, and myeloid leukemia cell lines. 
01-01-2007
bullet iconKumuthini J, Bessant C, Wilson P and Crowther D (2007). Gene regulatory network of human adipocyte differentiation. BMC Systems Biology, BioMed Central Ltd vol. 1, P57-P57.  
01-01-2007
bullet iconKumuthini J, Jouffe L and Bessant C (2007). Session 1-Microarray and Systems Biology I (Networks)-A Novel Graph Optimisation Algorithm for the Extraction of Gene Regulatory Networks from Temporal Microarray Data. Lecture Notes in Computer Science vol. 4414, 28-28.  
01-01-2007
bullet iconBabrah J, Lush R, Rye A, McCarthy K, Bessant C and Stone N (2007). Fourier transform infrared spectroscopic studies of lymphoma, lymphoid and myeloid leukaemia cell lines. 
01-01-2007

2006

bullet iconShadforth I and Bessant C (2006). Genome annotating proteomics pipelines: available tools. Expert Rev Proteomics vol. 3 (6), 621-629.  
01-12-2006
bullet iconShadforth I, Xu W, Crowther D and Bessant C (2006). GAPP: a fully automated software for the confident identification of human peptides from tandem mass spectra. J Proteome Res vol. 5 (10), 2849-2852.  
01-10-2006
bullet iconErnst W, Trummer E, Mead J, Bessant C, Strelec H, Katinger H and Hesse F (2006). Evaluation of a genomics platform for cross-species transcriptome analysis of recombinant CHO cells. Biotechnol J vol. 1 (6), 639-650.  
01-06-2006
bullet iconFend R, Kolk AHJ, Bessant C, Buijtels P, Klatser PR and Woodman AC (2006). Prospects for clinical application of electronic-nose technology to early detection of Mycobacterium tuberculosis in culture and sputum. J Clin Microbiol vol. 44 (6), 2039-2045.  
01-06-2006
bullet iconDunkley TPJ, Hester S, Shadforth IP, Runions J, Weimar T, Hanton SL, Griffin JL, Bessant C, Brandizzi F, Hawes C, Watson RB, Dupree P and Lilley KS (2006). Mapping the Arabidopsis organelle proteome. Proc Natl Acad Sci U S A vol. 103 (17), 6518-6523.  
25-04-2006
bullet iconSaini S, Bessant C, Lee-davey J and Malecha MM (2006). VOLTAMMETRIC DETECTION OF METABOLITES IN PHYSIOLOGICAL FLUIDS. 
22-03-2006
bullet iconSadowski PG, Dunkley TPJ, Shadforth IP, Dupree P, Bessant C, Griffin JL and Lilley KS (2006). Quantitative proteomic approach to study subcellular localization of membrane proteins. Nat Protoc vol. 1 (4), 1778-1789.  
01-01-2006
bullet iconLilley KS, Hawes C, Hanton SL, Dunkley TPJ, Runions J, Hester S, Weimar T, Shadforth IP, Bessant C, Dupree P and others (2006). Mapping the Arabidopsis organelle proteome. Proceedings of the National Academy of Sciences of the United States of America, Editor no identificado, 6518-6523.  
01-01-2006

2005

bullet iconShadforth I, Crowther D and Bessant C (2005). Protein and peptide identification algorithms using MS for use in high-throughput, automated pipelines. Proteomics vol. 5 (16), 4082-4095.  
01-11-2005
bullet iconShadforth IP, Dunkley TPJ, Lilley KS and Bessant C (2005). i-Tracker: for quantitative proteomics using iTRAQ. BMC Genomics vol. 6 
20-10-2005
bullet iconShadforth I, Todd K, Crowther D and Bessant C (2005). Determination of partial amino acid composition from tandem mass spectra for use in peptide identification strategies. Proteomics vol. 5 (7), 1787-1796.  
01-05-2005
bullet iconSAINI S, BESSANT C, LEE-DAVEY J, MALECHA M and others (2005). VOLTAMMETRIC DETECTION OF METABOLITES IN PHYSIOLOGICAL FLUIDS. 
07-01-2005
bullet iconShadforth I, Dunkley T, Lilley K, Crowther D and Bessant C (2005). Confident protein identification using the average peptide score method coupled with search-specific, ab initio thresholds. Rapid Commun Mass Spectrom vol. 19 (22), 3363-3368.  
01-01-2005
bullet iconMead JA, Bianco L and Bessant C (2005). the focus of attention in financial reporting. Abacus 
01-01-2005

2004

bullet iconFend R, Bessant C, Williams AJ and Woodman AC (2004). Monitoring haemodialysis using electronic nose and chemometrics. Biosens Bioelectron vol. 19 (12), 1581-1590.  
15-07-2004
bullet iconSaini S, Bessant C, Lee-Davey J and Malecha MM (2004). Voltammetric detection of metabolites in physiological fluids. 
28-06-2004
bullet iconRichards E, Bessant C and Saini S (2004). Simultaneous quantification of analytes in quaternary mixtures using dual pulse staircase voltammetry and genetically optimised neural networks. Analyst vol. 129 (4), 355-358.  
01-04-2004
bullet iconSaini S, Bessant C, Liedtke C and Leiferkus J (2004). DIAGNOSIS BY SENSING VOLATILE COMPONENTS. 
14-01-2004
bullet iconShadforth I, Crowther D and Bessant C (2004). Search-Space Reduction of a Non-Redundant Peptide Database. 
01-01-2004
bullet iconOduguwa A, Tiwari A, Roy R and Bessant C (2004). An Overview of Soft Computing Techniques Used in the Drug Discovery Process., Editors: Abraham A, Baets BD, Köppen M and Nickolay B. 
01-01-2004

2003

bullet iconMalecha M, Bessant C and Saini S (2003). Identification of oil contaminants on polymer coated beverage cans using fluorescence spectroscopy. Appl Spectrosc vol. 57 (8), 1042-1048.  
01-08-2003
bullet iconRichards E, Bessant C and Saini S (2003). A liquid handling system for the automated acquisition of data for training, validating and testing calibration models. Sensors and Actuators B: Chemical, Elsevier vol. 88, 149-154.  
01-01-2003
bullet iconBessant C and Richards E (2003). Neural networks for the calibration of voltammetric data. Nature-inspired methods in chemometrics: genetic algorithms and artificial neural networks: genetic algorithms and artificial neural networks, Elsevier vol. 23, 257-257.  
01-01-2003

2002

bullet iconSAINI S, BESSANT C, LIEDTKE C, LEIFERKUS J and others (2002). DIAGNOSIS BY SENSING VOLATILE COMPONENTS. 
01-11-2002
bullet iconMalecha M, Bessant C and Saini S (2002). Principal components analysis for the visualisation of multidimensional chemical data acquired by scanning Raman microspectroscopy. Analyst vol. 127 (9), 1261-1266.  
01-09-2002
bullet iconSaini S, Bessant C, Liedtke C and Leiferkus J (2002). Diagnosis by sensing volatile components. 
19-04-2002
bullet iconRichards E, Bessant C and Saini S (2002). Multivariate data analysis in electroanalytical chemistry. Electroanalysis, Wiley Online Library vol. 14, 1533-1542.  
01-01-2002
bullet iconRichards E, Bessant C and Saini S (2002). Optimisation of a neural network model for calibration of voltammetric data. Chemometrics and intelligent laboratory systems, Elsevier vol. 61, 35-49.  
01-01-2002
bullet iconMalecha M, Bessant C, Perry D and Saini S (2002). Identification of oil contaminants on polymer coated beverage cans using Raman spectroscopy. Analyst, Royal Society of Chemistry vol. 127, 297-303.  
01-01-2002

2001

bullet iconBrereton RG and Bessant C (2001). Simultaneous resolution of overlapping tailing peaks of Isomers using dual detector diode array liquid Chromatography electrospray mass spectrometry. Aegean Analytical Chemistry Conference
31-12-2001
bullet iconSaini S, Barr H and Bessant C (2001). Sniffing out disease using the artificial nose. Biologist (London) vol. 48 (5), 229-233.  
01-10-2001
bullet iconBessant C, Ritchie L, Saini S, Pahlavanpour B and Wilson G (2001). Chemometric evaluation of synchronous scan fluorescence spectroscopy for the determination of regulatory conformance and usage history of insulation oils. Applied spectroscopy, Society for Applied Spectroscopy vol. 55, 840-846.  
01-01-2001

2000

bullet iconRitchie LJ, Ferguson CP, Bessant C and Saini S (2000). A ten channel fibre-optic device for distributed sensing of underground hydrocarbon leakage. J Environ Monit vol. 2 (6), 670-673.  
01-12-2000
bullet iconSAINI S and BESSANT C (2000). ANALYSIS OF MIXTURES. 
14-04-2000
bullet iconBessant C and Saini S (2000). A chemometric analysis of dual pulse staircase voltammograms obtained in mixtures of ethanol, fructose and glucose. Journal of electroanalytical chemistry, Elsevier vol. 489, 76-83.  
01-01-2000

1999

bullet iconBessant C and Saini S (1999). Simultaneous determination of ethanol, fructose, and glucose at an unmodified platinum electrode using artificial neural networks. Analytical Chemistry, ACS Publications vol. 71, 2806-2813.  
01-01-1999
bullet iconBrereton R and others (1999). Integrated processing of triply coupled diode array liquid chromatography electrospray mass spectrometric signals by chemometric methods. Analyst, Royal Society of Chemistry vol. 124, 1733-1744.  
01-01-1999

1997

bullet iconBessant C and Saini S (1997). An object oriented approach to electroanalytical technique implementation. Electroanalysis, Wiley Online Library vol. 9, 926-931.  
01-01-1997

Grants

solid heart iconGrants of specific relevance to the Centre for Molecular Cell Biology
bullet iconAI driven Omics Data Integration and Transfer Learning for Target and Biomarker Identification
Conrad Bessant
£127,935 BBSRC Biotechnology and Biological Sciences Research Council (01-10-2024 - 30-09-2028)
solid heart iconBBSRC AIDD CTP CASE Award: Syed Zayyan Masud
Conrad Bessant
£21,600 Nxera Pharma UK Ltd (01-10-2024 - 30-09-2028)
bullet iconMechanisms underlying preterm birth in women with HIV in rural Zimbabwe
Andrew Prendergast, Ruairi Robertson, Melanie Smuk, Claire Bourke, Nikolaos Donos, Robert Allaker, Abish Stephen, Conrad Bessant, Stefaan Verbruggen and Tina Chowdhury
£1,142,315 MRC Medical Research Council (01-05-2024 - 30-04-2027)
bullet iconMartina Occhetta CTP Studentship - Exscientia Funded
Conrad Bessant and Emma Tjong
£8,600 EXSCIENTIA LIMITED (01-10-2023 - 30-09-2027)
bullet iconTG: Target identification from multiomics data using systems biology and machine learning approaches
Conrad Bessant
£125,917 BBSRC Biotechnology and Biological Sciences Research Council (01-10-2023 - 30-09-2027)
bullet iconCTP Training Grant: Lewis Palmer
Conrad Bessant
£123,829 BBSRC Biotechnology and Biological Sciences Research Council (01-10-2022 - 12-11-2026)
bullet iconBBSRC AIDD CTP CASE Award: Lewis Palmer: “Prioritising Drug Targets in non-canonical pathways from multi-omic data
Conrad Bessant
£10,400 Merck (26-09-2022 - 25-09-2026)
bullet iconSurvey and BIOinformatic review of fluid-tissue proteomics: novel biomarkers for ALS
Andrea Malaspina and Conrad Bessant
£188,946 Barts and the London Charity (01-09-2020 - 31-08-2025)


bullet iconBid for MRC Industrial Strategy PhD Studentship 2018
Conrad Bessant
£93,462 MRC Medical Research Council (01-10-2018 - 31-03-2022)