Dr Matthew Day

Day M, Tetik B, Parlak M, Almeida-Hernández Y, Räschle M, Kaschani F, Siegert H, Marko A, Sanchez-Garcia E, Kaiser M, Barker IA, Pearl LH, Oliver AW and Boos D (2024). TopBP1 utilises a bipartite GINS binding mode to support genome replication. Nature Communications, Springer Nature vol. 15 (1) 
27-02-2024

Day M, Oliver AW and Pearl LH (2022). Structure of the human RAD17–RFC clamp loader and 9–1–1 checkpoint clamp bound to a dsDNA–ssDNA junction. Nucleic Acids Research, Oxford University Press (OUP) vol. 50 (14), 8279-8289.  
12-07-2022

Day M, Oliver AW and Pearl LH (2021). Phosphorylation-dependent assembly of DNA damage response systems and the central roles of TOPBP1. DNA Repair, Elsevier vol. 108 
29-09-2021

Prabhakar AT, James CD, Das D, Otoa R, Day M, Burgner J, Fontan CT, Wang X, Glass SH, Wieland A, Donaldson MM, Bristol ML, Li R, Oliver AW, Pearl LH, Smith BO and Morgan IM (2021). CK2 Phosphorylation of Human Papillomavirus 16 E2 on Serine 23 Promotes Interaction with TopBP1 and Is Critical for E2 Interaction with Mitotic Chromatin and the Viral Life Cycle. mBio, American Society for Microbiology vol. 12 (5), 10.1128/mbio.01163-10.1128/mbio.01121.  
21-09-2021

Day M, Parry-Morris S, Houghton-Gisby J, Oliver AW and Pearl LH (2021). Structural basis for recruitment of the CHK1 DNA damage kinase by the CLASPIN scaffold protein. Structure, Elsevier vol. 29 (6), 531-539.e3.  
30-03-2021

Bigot N, Day M, Baldock RA, Watts FZ, Oliver AW and Pearl LH (2019). Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint. eLife, eLife vol. 8 
28-05-2019

Leimbacher P-A, Jones SE, Shorrocks A-MK, de Marco Zompit M, Day M, Blaauwendraad J, Bundschuh D, Bonham S, Fischer R, Fink D, Kessler BM, Oliver AW, Pearl LH, Blackford AN and Stucki M (2019). MDC1 Interacts with TOPBP1 to Maintain Chromosomal Stability during Mitosis. Molecular Cell, Elsevier vol. 74 (3), 571-583.e8.  
18-03-2019

Day M, Rappas M, Ptasinska K, Boos D, Oliver AW and Pearl LH (2018). BRCT domains of the DNA damage checkpoint proteins TOPBP1/Rad4 display distinct specificities for phosphopeptide ligands. eLife, eLife vol. 7 
08-10-2018

Baldock RA, Day M, Wilkinson OJ, Cloney R, Jeggo PA, Oliver AW, Watts FZ and Pearl LH (2015). ATM Localization and Heterochromatin Repair Depend on Direct Interaction of the 53BP1-BRCT2 Domain with γH2AX. Cell Reports, Elsevier vol. 13 (10), 2081-2089.  
25-11-2015

Qu M, Rappas M, Wardlaw CP, Garcia V, Ren J-Y, Day M, Carr AM, Oliver AW, Du L-L and Pearl LH (2013). Phosphorylation-Dependent Assembly and Coordination of the DNA Damage Checkpoint Apparatus by Rad4TopBP1. Molecular Cell, Elsevier vol. 51 (6), 723-736.  
01-09-2013