Dr Zheren Zhang
Lecturer in Biotechnology
School of Biological and Behavioural Sciences
Queen Mary University of London
Research
Synthetic Biology, Microbial Evolution, Division of Labour, Biotechnology, Pollutant Degradation, Antibiotic Production
Interests
I use synthetic biology and evolutionary biology to address fundamental and applied biotechnological challenges in microorganisms, including
Streptomyces and
Pseudomonas putida. One of my research focuses is understanding the evolution of division of labour in natural microbial systems and exploring how these principles can be harnessed for pollutant degradation and the production of valuable compounds.
Publications
Publications of specific relevance to the Centre for Molecular Cell Biology
2022
Mutational meltdown of putative microbial altruists in Streptomyces coelicolor coloniesZhang Z Shitut S Claushuis B Claessen D Rozen DE
Nature Communications,
Springer Nature vol. 13 (1)
27-04-20222020
Genome rearrangements and megaplasmid loss in the filamentous bacterium Kitasatospora viridifaciens are associated with protoplast formation and regenerationRamijan K Zhang Z van Wezel GP Claessen D
Antonie Van Leeuwenhoek,
Springer Nature vol. 113 (6), 825-837.
14-02-2020 Antibiotic production in Streptomyces is organized by a division of labor through terminal genomic differentiationZhang Z Du C de Barsy F Liem M Liakopoulos A van Wezel GP Choi YH Claessen D et al.
Science Advances,
American Association For The Advancement of Science (Aaas) vol. 6 (3)
15-01-2020 Group Benefits from Genomic Instability A Tale of Antibiotic Warriors in Streptomyces 01-01-2020 2018
Stress-induced formation of cell wall-deficient cells in filamentous actinomycetesRamijan K Ultee E Willemse J Zhang Z Wondergem JAJ van der Meij A Heinrich D Briegel A et al.
Nature Communications,
Springer Nature vol. 9 (1)
04-12-2018 2017
The evolution of no-cost resistance at sub-MIC concentrations of streptomycin in Streptomyces coelicolorWesthoff S van Leeuwe TM Qachach O Zhang Z van Wezel GP Rozen DE
The Isme Journal: Multidisciplinary Journal of Microbial Ecology,
Oxford University Press (OUP) vol. 11 (5), 1168-1178.
17-01-2017 2016
Understanding Microbial Divisions of LaborZhang Z Claessen D Rozen DE
Frontiers in Microbiology,
Frontiers vol. 7
21-12-2016 2013
Cloning and functional characterization of the pig (Sus scrofa) organic anion transporting polypeptide 1a2Yu Y Liu X Zhang Z Xiao Y Hong M
Xenobiotica,
Taylor & Francis vol. 43 (8), 738-744.
16-01-2013 2012
Identification of Multiple Binding Sites for Substrate Transport in Bovine Organic Anion Transporting Polypeptide 1a2Liu X Huang J Sun Y Zhan K Zhang Z Hong M
Drug Metabolism and Disposition,
Elsevier vol. 41 (3), 602-607.
19-12-2012 Divergent spontaneous antibiotic-resistance evolution confers reciprocal and exploitable collateral sensitivity effectsLiakopoulos A Tandar ST Hoogendijk IV Fragkiskou E Zhang Z Vriesendorp B Aulin LBS van Hasselt JGC et al.
In
Biorxiv
Research Group
