Dr Pamela Swiatlowska
Postdoctoral Research Assistant
School of Engineering and Materials Science
Queen Mary University of London
Research
Cardiovascular Mechanobiology, Heart Failure, Atherosclerosis, Nuclear remodelling
Interests
My research focuses on cardiovascular mechanobiology, specifically how cells sense mechanical forces, such as blood pressure, that affect nuclear structure, chromatin organization, and disease progression in heart failure, atherosclerosis, and aging.
Multi-disciplinary Research | Innovation | Translational Research | Sustainable Lab Work | EDI
Publications
Publications of specific relevance to the Centre for Bioengineering
2023
Cardiovascular Mechano-Epigenetics: Force-Dependent Regulation of Histone Modifications and Gene RegulationSwiatlowska P Iskratsch T
Cardiovascular Drugs and Therapy,
Springer Nature vol. 38 (2), 215-222.
18-01-2023 2022
Intrinsic cell rheology drives junction maturationSri-Ranjan K Sanchez-Alonso JL Swiatlowska P Rothery S Gerlach S Koeninger D Merkel R Stevens MM et al.
Nature Communications,
Springer Nature vol. 13 (1)
17-08-2022Pressure and stiffness sensing together regulate vascular smooth muscle cell phenotype switchingSwiatlowska P Sit B Feng Z Marhuenda E Xanthis I Zingaro S Ward M Zhou X et al.
Science Advances,
American Association For The Advancement of Science (Aaas) vol. 8 (15)
15-04-2022 2021
Cardiovascular mechanobiology—a Special Issue to look at the state of the art and the newest insights into the role of mechanical forces in cardiovascular development, physiology and diseaseSwiatlowska P Iskratsch T
Biophysical Reviews,
Springer Nature vol. 13 (5), 575-577.
11-09-2021 Tools for studying and modulating (cardiac muscle) cell mechanics and mechanosensing across the scalesSwiatlowska P Iskratsch T
Biophysical Reviews,
Springer Nature vol. 13 (5), 611-623.
05-09-2021 Announcing the call for the Special Issue on “Cardiovascular mechanobiology—a special issue to look at the state of the art and the newest insights into the role of mechanical forces in cardiovascular development, physiology, and disease”Swiatlowska P Iskratsch T
Biophysical Reviews,
Springer Nature vol. 13 (3), 307-308.
03-05-2021 2020
Microtubules regulate cardiomyocyte transversal Young’s modulusSwiatlowska P Sanchez-Alonso JL Novak P
Proceedings of The National Academy of Sciences of The United States of America,
Proceedings of The National Academy of Sciences vol. 117 (6), 2764-2766.
27-01-2020 2019
Single cell mechanics in failing heart: role of microtubules and mitochondria re-arrangementSwiatlowska PP Sanchez-Alonso J Wright P Bello S Gorelik J
EUROPEAN JOURNAL OF HEART FAILURE. vol. 21, 316-316.
01-01-2019
Research Group
