Dr Elisabeth Busch-Nentwich

Research

Functional Genomics, Disease Modelling, Developmental Biology

Publications

Publications of specific relevance to the Centre for Evolutionary and Functional Genomics

2024

Zebrafish are resilient to the loss of major diacylglycerol acyltransferase enzymes
Wilson MH Hensley MR Shen M-C Lu H-Y Quinlivan VH
Journal of Biological Chemistry, Elsevier Bv, 107973-107973.  

DOI 10.1016/j.jbc.2024.107973

QMRO

05-11-2024

Pla2g12b drives expansion of triglyceride-rich lipoproteins
Thierer JH Foresti O Yadav PK Wilson MH Moll TOC Shen M-C Busch-Nentwich EM Morash M et al.
Nature Communications, Springer Nature vol. 15 (1), 2095-2095.  

DOI 10.1038/s41467-024-46102-4

QMRO

07-03-2024

Digenic inheritance involving a muscle-specific protein kinase and the giant titin protein causes a skeletal muscle myopathy
Töpf A Cox D Zaharieva IT Di Leo V Sarparanta J Jonson PH Sealy IM Smolnikov A et al.
Nature Genetics, Springer Nature vol. 56 (3), 395-407.  

DOI 10.1038/s41588-023-01651-0

QMRO

01-03-2024

Transcriptional profiling of zebrafish identifies host factors controlling susceptibility to Shigella flexneri
Torraca V White RJ Sealy IM Mazon-Moya M Duggan G
Disease Models & Mechanisms, The Company of Biologists vol. 17 (1) 

DOI 10.1242/dmm.050431

QMRO

01-01-2024

2023

Selenoprotein deficiency disorder predisposes to aortic aneurysm formation
Schoenmakers E Marelli F Jørgensen HF Visser WE Moran C Groeneweg S Avalos C Jurgens SJ et al.
Nature Communications, Springer Nature vol. 14 (1), 7994-7994.  

DOI 10.1038/s41467-023-43851-6

QMRO

02-12-2023

Gaucher disease protects against tuberculosis
Fan J Hale VL Lelieveld LT Whitworth LJ Busch-Nentwich EM Troll M Edelstein PH Roca FJ et al.
Proceedings of The National Academy of Sciences of The United States of America, Proceedings of The National Academy of Sciences vol. 120 (7), e2217673120-e2217673120.  

DOI 10.1073/pnas.2217673120

QMRO

06-02-2023

P38 Mediates Tumor Suppression through Reduced Autophagy and Actin Cytoskeleton Changes in NRAS-Mutant Melanoma
Banik I Ghosh A Beebe E Burja B Frank Bertoncelj M Dooley CM Markkanen E
Cancers, Mdpi vol. 15 (3), 877-877.  

DOI 10.3390/cancers15030877

QMRO

31-01-2023

2022

Conserved roles for Hnf4 family transcription factors in zebrafish development and intestinal function
Heppert JK Lickwar CR Tillman MC Davis BR Lu H-Y Chen W
Genetics, Oxford University Press (OUP) vol. 222 (4), iyac133-iyac133.  

DOI 10.1093/genetics/iyac133

QMRO

11-10-2022

mTOR-regulated mitochondrial metabolism limits mycobacterium-induced cytotoxicity
Pagán AJ Lee LJ Edwards-Hicks J Moens CB Busch-Nentwich EM Ramakrishnan L
Cell, Elsevier vol. 185 (20), 3720-3738.e13.  

DOI 10.1016/j.cell.2022.08.018

QMRO

01-09-2022

Loss of slc39a14 causes simultaneous manganese hypersensitivity and deficiency in zebrafish
Tuschl K White RJ Trivedi C Valdivia LE Niklaus S Dadswell C González-Méndez R Sealy IM
Disease Models and Mechanisms, The Company of Biologists vol. 15 (6) 

DOI 10.1242/dmm.044594

QMRO

15-06-2022

Allele-specific gene expression can underlie altered transcript abundance in zebrafish mutants
White RJ Mackay E Wilson SW
Elife, Elife Sciences Publications vol. 11 

DOI 10.7554/ELIFE.72825

QMRO

17-02-2022

Ankk1 Loss of Function Disrupts Dopaminergic Pathways in Zebrafish
Leggieri A García-González J Torres-Perez JV Havelange W Hosseinian S Mech AM Keatinge M Busch-Nentwich EM et al.
Frontiers in Neuroscience, Frontiers vol. 16 

DOI 10.3389/fnins.2022.794653

QMRO

08-02-2022

Translational relevance of forward genetic screens in animal models for the study of psychiatric disease
Sheardown E Mech AM Petrazzini MEM Leggieri A Gidziela A Hosseinian S Sealy IM Torres-Perez JV et al.
Neuroscience and Biobehavioral Reviews, Elsevier vol. 135 

DOI 10.1016/j.neubiorev.2022.104559

QMRO

04-02-2022

Behavioral and Gene Regulatory Responses to Developmental Drug Exposures in Zebrafish
Mech AM Merteroglu M Sealy IM Teh M-T White RJ Havelange W Brennan CH Busch-Nentwich EM
Frontiers in Psychiatry, Frontiers vol. 12 

DOI 10.3389/fpsyt.2021.795175

QMRO

10-01-2022

Total Nucleic Acid Extraction from Single Zebrafish Embryos for Genotyping and RNA-seq
Wali N Merteroglu M White RJ
Bio-Protocol, Bio-Protocol vol. 12 (1) 

DOI 10.21769/BioProtoc.4284

QMRO

05-01-2022

Research Group

PhD Students

• Srishti Arya
  Transforming Meiofaunal Molecular Systematics and Community Ecology Through Nanopore-Based Transcriptomics.
• Luisa Fernanda Cerda Osnaya
  Molecular Genetic Mechanisms of Fibromyalgia
• Yeahji Jeong
  High Resolution Molecular Diagnostics to Improve Pollinator Health
• Kite Jones
  Functional Characterisation of Neuropeptides That Act as Ligands For Secretin-Type Receptors in An Echinoderm.
• Pavol Kramár
  Investigating Mechanisms of Functional Compensation Between Paralogous Genes in Embryonic Development
• Zoe O'Neill
  Epigenetic Determination of Phenotypic Plasticity in The Honey Bee
• Tian Qiu
  The Role of The Chromatin Modifier Kdm2aa in Melanoma Formation
• Roudin Sarama
  Human Genetic Adaptation to Pathogens During The Holocene as Unveiled by Ancient DNA and Machine Learning
• Jingcheng Wei
  The Evolution and Control of Early Spiral Cleavage
• Haoran Zhang
  Molecular Drivers of Cin Seen in Aggressive Cancers

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