Prof Laurent Frantz
Professor in Animal Paleogenomics
School of Biological and Behavioural Sciences
Queen Mary University of London
Queen Mary University of London
Research
Paleogenomics, Animal Domestication, Ancient DNA, Conservation biology
Interests
My group is broadly interested in evolutionary genomics, archaeology, conservation biology and sustainable agriculture. We exploit the power of ancient and modern genomics to contrast current patterns of genetic diversity to those in the past: this allows us to track evolutionary processes including artificial selection, extinction, speciation and domestication through time.Current projects focus on reconstructing the evolutionary history of domestic species such as dogs, pigs, chickens, cats, cattle and sheep. Our group is also involved in multiple projects that study past extinction processes, and epidemics in canids, bovids and suids in wild and domestic populations, with the aim to extend this knowledge to tackle current conservation and agricultural challenges.
Publications
Publications of specific relevance to the Centre for Evolutionary and Functional Genomics2024
Ancient mitogenomes from Pre-Pottery Neolithic Central Anatolia and the effects of a Late Neolithic bottleneck in sheep (Ovis aries)Sandoval-Castellanos E, Hare AJ, Lin AT, Dimopoulos EA, Daly KG, Geiger S, Mullin VE, Wiechmann I, Mattiangeli V, Lühken G, Zinovieva NA, Zidarov P, Çakırlar C, Stoddart S, Orton D, Bulatović J, Mashkour M, Sauer EW, Horwitz LK, Horejs B, et al.
Science Advances, American Association For The Advancement of Science (Aaas) vol. 10 (15)
12-04-2024
Patagonian partnerships: the extinct Dusicyon avus and its interaction with prehistoric human communitiesAbbona CC, Lebrasseur O, Prevosti FJ, Peralta E, Venanzi LG, Frantz L, Larson G, Gil AF and Neme GA
Royal Society Open Science, The Royal Society vol. 11 (4)
01-04-2024
Genomic insights into the population history and adaptive traits of Latin American Criollo cattleWard JA, Ng'ang'a SI, Randhawa IAS, McHugo GP, O'Grady JF, Flórez JM, Browne JA, O’Brien AMP, Landaeta-Hernández AJ, Garcia JF, Sonstegard TS, Frantz LAF, Salter-Townshend M and MacHugh DE
Royal Society Open Science, The Royal Society vol. 11 (3)
01-03-2024
A compendium of genetic regulatory effects across pig tissuesTeng J, Gao Y, Yin H, Bai Z, Liu S, Zeng H, Bai L, Cai Z, Zhao B, Li X, Xu Z, Lin Q, Pan Z, Yang W, Yu X, Guan D, Hou Y, Keel BN, Rohrer GA, Lindholm-Perry AK, et al.
Nature Genetics, Springer Nature vol. 56 (1), 112-123.
01-01-2024
2023
Ancient chicken remains reveal the origins of virulence in Marek’s disease virusFiddaman SR, Dimopoulos EA, Lebrasseur O, du Plessis L, Vrancken B, Charlton S, Haruda AF, Tabbada K, Flammer PG, Dascalu S, Marković N, Li H, Franklin G, Symmons R, Baron H, Daróczi-Szabó L, Shaymuratova DN, Askeyev IV, Putelat O, Sana M, et al.
Science, American Association For The Advancement of Science (Aaas) vol. 382 (6676), 1276-1281.
14-12-2023
The history of Coast Salish “woolly dogs” revealed by ancient genomics and Indigenous KnowledgeLin AT, Hammond-Kaarremaa L, Liu H-L, Stantis C, McKechnie I, Pavel M, Pavel SSM, Wyss SSÁ, Sparrow DQ, Carr K, Aninta SG, Perri A, Hartt J, Bergström A, Carmagnini A, Charlton S, Dalén L, Feuerborn TR, France CAM, Gopalakrishnan S, et al.
Science, American Association For The Advancement of Science (Aaas) vol. 382 (6676), 1303-1308.
14-12-2023
A pangenome graph reference of 30 chicken genomes allows genotyping of large and complex structural variantsRice ES, Alberdi A, Alfieri J, Athrey G, Balacco JR, Bardou P, Blackmon H, Charles M, Cheng HH, Fedrigo O, Fiddaman SR, Formenti G, Frantz LAF, Gilbert MTP, Hearn CJ, Jarvis ED, Klopp C, Marcos S, Mason AS, Velez-Irizarry D, et al.
Bmc Biology, Springer Nature vol. 21 (1)
22-11-2023
Author Correction: Genome sequencing of 2000 canids by the Dog10K consortium advances the understanding of demography, genome function and architectureMeadows JRS, Kidd JM, Wang G-D, Parker HG, Schall PZ, Bianchi M, Christmas MJ, Bougiouri K, Buckley RM, Hitte C, Nguyen AK, Wang C, Jagannathan V, Niskanen JE, Frantz LAF, Arumilli M, Hundi S, Lindblad-Toh K, Ginja C, Agustina KK, et al.
Genome Biology, Springer Nature vol. 24 (1)
07-11-2023
Genetic swamping of the critically endangered Scottish wildcat was recent and accelerated by diseaseHoward-McCombe J, Jamieson A, Carmagnini A, Russo I-RM, Ghazali M, Campbell R, Driscoll C, Murphy WJ, Nowak C, O'Connor T, Tomsett L, Lyons LA, Muñoz-Fuentes V, Bruford MW, Kitchener AC, Larson G, Frantz L, Senn H, Lawson DJ and Beaumont MA
Current Biology, Elsevier vol. 33 (21), 4761-4769.e5.
01-11-2023
Limited historical admixture between European wildcats and domestic catsJamieson A, Carmagnini A, Howard-McCombe J, Doherty S, Hirons A, Dimopoulos E, Lin AT, Allen R, Anderson-Whymark H, Barnett R, Batey C, Beglane F, Bowden W, Bratten J, De Cupere B, Drew E, Foley NM, Fowler T, Fox A, Geigl E-M, et al.
Current Biology, Elsevier vol. 33 (21), 4751-4760.e14.
01-11-2023
Genome sequencing of 2000 canids by the Dog10K consortium advances the understanding of demography, genome function and architectureMeadows JRS, Kidd JM, Wang G-D, Parker HG, Schall PZ, Bianchi M, Christmas MJ, Bougiouri K, Buckley RM, Hitte C, Nguyen AK, Wang C, Jagannathan V, Niskanen JE, Frantz LAF, Arumilli M, Hundi S, Lindblad-Toh K, Ginja C, Agustina KK, et al.
Genome Biology, Springer Nature vol. 24 (1)
15-08-2023
The extinct Sicilian wolf shows a complex history of isolation and admixture with ancient dogsCiucani MM, Ramos-Madrigal J, Hernández-Alonso G, Carmagnini A, Aninta SG, Sun X, Scharff-Olsen CH, Lanigan LT, Fracasso I, Clausen CG, Aspi J, Kojola I, Baltrūnaitė L, Balčiauskas L, Moore J, Åkesson M, Saarma U, Hindrikson M, Hulva P, Bolfíková BČ, et al.
Iscience, Elsevier vol. 26 (8)
10-07-2023
Hybrid origin of a primate, the gray snub-nosed monkeyWu H, Wang Z, Zhang Y, Frantz L, Roos C, Irwin DM, Zhang C, Liu X, Wu D, Huang S, Gu T, Liu J and Yu L
Science, American Association For The Advancement of Science (Aaas) vol. 380 (6648)
02-06-2023
Fourth Report on Chicken Genes and Chromosomes 2022.Smith J, Alfieri JM, Anthony N, Arensburger P, Athrey GN, Balacco J, Balic A, Bardou P, Barela P, Bigot Y, Blackmon H, Borodin PM, Carroll R, Casono MC, Charles M, Cheng H, Chiodi M, Cigan L, Coghill LM, Crooijmans R, et al.
Cytogenetics and Genome Research, Karger Publishers
30-01-2023
2022
ifCNV: A novel isolation-forest-based package to detect copy-number variations from various targeted NGS datasetsCabello-Aguilar S, Vendrell JA, Van Goethem C, Brousse M, Gozé C, Frantz L and Solassol J
Molecular Therapy - Nucleic Acids, Cell Press vol. 30, 174-183.
13-12-2022
Safeguarding Imperiled Biodiversity and Evolutionary Processes in the Wallacea Center of EndemismStruebig MJ, Aninta SG, Beger M, Bani A, Barus H, Brace S, Davies ZG, De Brauwer M, Diele K, Djakiman C, Djamaluddin R, Drinkwater R, Dumbrell A, Evans D, Fusi M, Herrera-Alsina L, Iskandar DT, Jompa J, Juliandi B, Lancaster LT, et al.
Bioscience, Oxford University Press vol. 72 (11), 1118-1130.
19-10-2022
HAYSTAC: A Bayesian framework for robust and rapid species identification in high-throughput sequencing dataDimopoulos EA, Carmagnini A, Velsko IM, Warinner C, Larson G, Frantz LAF and Irving-Pease EK
Plos Computational Biology, Public Library of Science, 2020.12.16.419085-2020.12.16.419085.
30-09-2022
The genomic history and global expansion of domestic donkeysTodd ET, Tonasso-Calvière L, Chauvey L, Schiavinato S, Fages A, Seguin-Orlando A, Clavel P, Khan N, Pardal LP, Rosa LP, Librado P, Ringbauer H, Verdugo M, Southon J, Aury JM, Perdereau A, Vila E, Marzullo M, Prato O, Tecchiati U, et al.
Science, American Association For The Advancement of Science vol. 377 (6611), 1172-1180.
08-09-2022
Uncovering the enigmatic evolution of bears in greater depth: The hybrid origin of the Asiatic black bearZou T, Kuang W, Yin T, Frantz L, Zhang C, Liu J, Wu H and Yu L
Proceedings of The National Academy of Sciences of The United States of America, Proceedings of The National Academy of Sciences vol. 119 (31)
18-07-2022
Genome-wide local ancestry and evidence for mitonuclear coadaptation in African hybrid cattle populationsWard JA, McHugo GP, Dover MJ, Hall TJ, Ng'ang'a SI, Sonstegard TS, Bradley DG, Frantz LAF, Salter-Townshend M and MacHugh DE
Iscience, Cell Press vol. 25 (7)
15-07-2022
Grey wolf genomic history reveals a dual ancestry of dogsBergström A, Stanton DWG, Taron UH, Frantz L, Sinding M-HS, Ersmark E, Pfrengle S, Cassatt-Johnstone M, Lebrasseur O, Girdland-Flink L, Fernandes DM, Ollivier M, Speidel L, Gopalakrishnan S, Westbury MV, Ramos-Madrigal J, Feuerborn TR, Reiter E, Gretzinger J, Münzel SC, et al.
Nature, Springer Nature vol. 607 (7918), 313-320.
29-06-2022
The biocultural origins and dispersal of domestic chickensPeters J, Lebrasseur O, Irving-Pease EK, Paxinos PD, Best J, Smallman R, Callou C, Gardeisen A, Trixl S, Frantz L, Sykes N, Fuller DQ and Larson G
Proceedings of The National Academy of Sciences, National Academy of Sciences vol. 119 (24)
06-06-2022
Natural and human-driven selection of a single non-coding body size variant in ancient and modern canidsPlassais J, vonHoldt BM, Parker HG, Carmagnini A, Dubos N, Papa I, Bevant K, Derrien T, Hennelly LM, Whitaker DT, Harris AC, Hogan AN, Huson HJ, Zaibert VF, Linderholm A, Haile J, Fest T, Habib B, Sacks BN, Benecke N, et al.
Current Biology, Elsevier vol. 32 (4), 889-897.e9.
28-02-2022
2021
Adaptation and Cryptic Pseudogenization in Penguin Toll-Like ReceptorsFiddaman SR, Vinkler M, Spiro SG, Levy H, Emerling CA, Boyd AC, Dimopoulos EA, Vianna JA, Cole TL, Pan H, Fang M, Zhang G, Hart T, Frantz LAF and Smith AL
Molecular Biology and Evolution, Oxford University Press vol. 39 (1)
13-12-2021
Population genomic, olfactory, dietary, and gut microbiota analyses demonstrate the unique evolutionary trajectory of feral pigsPetrelli S, Buglione M, Maselli V, Troiano C, Larson G, Frantz L, Manin A, Ricca E, Baccigalupi L, Wright D, Pietri C and Fulgione D
Molecular Ecology, Wiley vol. 31 (1), 220-237.
31-10-2021
Kouprey (Bos sauveli) genomes unveil polytomic origin of wild Asian BosSinding M-HS, Ciucani MM, Ramos-Madrigal J, Carmagnini A, Rasmussen JA, Feng S, Chen G, Vieira FG, Mattiangeli V, Ganjoo RK, Larson G, Sicheritz-Pontén T, Petersen B, Frantz L, Gilbert MTP and Bradley DG
Iscience, Elsevier vol. 24 (11)
06-10-2021
Modern Siberian dog ancestry was shaped by several thousand years of Eurasian-wide trade and human dispersalFeuerborn TR, Carmagnini A, Losey RJ, Nomokonova T, Askeyev A, Askeyev I, Askeyev O, Antipina EE, Appelt M, Bachura OP, Beglane F, Bradley DG, Daly KG, Gopalakrishnan S, Murphy Gregersen K, Guo C, Gusev AV, Jones C, Kosintsev PA, Kuzmin YV, et al.
Proceedings of The National Academy of Sciences of The United States of America, Proceedings of The National Academy of Sciences vol. 118 (39)
20-09-2021
Pleistocene origins, western ghost lineages, and the emerging phylogeographic history of the red wolf and coyoteSacks BN, Mitchell KJ, Quinn CB, Hennelly LM, Sinding MS, Statham MJ, Preckler‐Quisquater S, Fain SR, Kistler L, Vanderzwan SL, Meachen JA, Ostrander EA and Frantz LAF
Molecular Ecology, Wiley vol. 30 (17), 4292-4304.
07-07-2021
Capitalizing on the Potential of South African Indigenous Beef Cattle Breeds: A ReviewVan Marle-Köster E, Visser C, Sealy J and Frantz L
Sustainability, Mdpi vol. 13 (8)
15-04-2021
A Zooarchaeological and Molecular Assessment of Ancient Chicken Remains from RussiaLebrasseur O, Department of Archaeology CAE, Shaymuratova DN, Askeyev AO, Asylgaraeva GS, Frantz L, Larson G, Askeyev OV, Askeyev IV, Wealth TAOSIOPIEAM, Khalikov TAOSIOANAAK, University of Munich LM, University of London M and School of Archaeology UOO
Поволжская Археология, Tatarstan Academy of Sciences vol. 1 (35), 216-231.
25-03-2021
Dog domestication and the dual dispersal of people and dogs into the AmericasPerri AR, Feuerborn TR, Frantz LAF, Larson G, Malhi RS, Meltzer DJ and Witt KE
Proceedings of The National Academy of Sciences of The United States of America vol. 118 (6)
09-02-2021
Dire wolves were the last of an ancient New World canid lineagePerri AR, Mitchell KJ, Mouton A, Álvarez-Carretero S, Hulme-Beaman A, Haile J, Jamieson A, Meachen J, Lin AT, Schubert BW, Ameen C, Antipina EE, Bover P, Brace S, Carmagnini A, Carøe C, Samaniego Castruita JA, Chatters JC, Dobney K, dos Reis M, et al.
Nature, Springer Nature vol. 591 (7848), 87-91.
13-01-2021
Genomes reveal selective sweeps in kiang and donkey for high-altitude adaptationZeng L, Liu H-Q, Tu X-L, Ji C-M, Gou X, Esmailizadeh A, Wang S, Wang M-S, Wang M-C, Li X-L, Charati H, Adeola AC, Adedokun RAM, Oladipo O, Olaogun SC, Sanke OJ, F. MG, Ommeh SC, Agwanda B, Lichoti JK, et al.
动物学研究, Zoological Research vol. 42 (4), 450-460.
01-01-2021
Reconsidering domestication from a process archaeology perspectiveBogaard A, Allaby R, Arbuckle BS, Bendrey R, Crowley S, Cucchi T, Denham T, Frantz L, Fuller D, Gilbert T, Karlsson E, Manin A, Marshall F, Mueller N, Peters J, Stépanoff C, Weide A and Larson G
World Archaeology, Taylor & Francis vol. 53 (1), 56-77.
01-01-2021
2020
Genetic Diversity, Inbreeding Level, and Genetic Load in Endangered Snub-Nosed Monkeys (Rhinopithecus)Kuang W, Hu J, Wu H, Fen X, Dai Q, Fu Q, Xiao W, Frantz L, Roos C, Nadler T, Irwin DM, Zhou L, Yang X and Yu L
Frontiers in Genetics, Frontiers vol. 11
15-12-2020
Addendum: Genomic analysis on pygmy hog reveals extensive interbreeding during wild boar expansionLiu L, Bosse M, Megens HJ, Frantz LAF, Lee YL, Irving-Pease EK, Narayan G, Groenen MAM and Madsen O
Nature Communications vol. 11 (1)
01-12-2020
Genetic origins and diversity of bushpigs from Madagascar (Potamochoerus larvatus, family Suidae)Lee C, Day J, Goodman SM, Pedrono M, Besnard G, Frantz L, Taylor PJ, Herrera MJ and Gongora J
Scientific Reports, Springer Nature vol. 10 (1)
26-11-2020
Origins and genetic legacy of prehistoric dogsBergström A, Frantz L, Schmidt R, Ersmark E, Lebrasseur O, Girdland-Flink L, Lin AT, Storå J, Sjögren KG, Anthony D, Antipina E, Amiri S, Bar-Oz G, Bazaliiskii VI, Bulatović J, Brown D, Carmagnini A, Davy T, Fedorov S, Fiore I, et al.
Science (New York, N.Y.) vol. 370 (6516), 557-564.
30-10-2020
Genomes of Pleistocene Siberian Wolves Uncover Multiple Extinct Wolf LineagesRamos-Madrigal J, Sinding M-HS, Carøe C, Mak SST, Niemann J, Castruita JAS, Fedorov S, Kandyba A, Germonpré M, Bocherens H, Feuerborn TR, Pitulko VV, Pavlova EY, Nikolskiy PA, Kasparov AK, Ivanova VV, Larson G, Frantz LAF, Willerslev E, Meldgaard M, et al.
Current Biology, Elsevier vol. 31 (1), 198-206.e8.
29-10-2020
863 genomes reveal the origin and domestication of chickenWang MS, Thakur M, Peng MS, Jiang Y, Frantz LAF, Li M, Zhang JJ, Wang S, Peters J, Otecko NO, Suwannapoom C, Guo X, Zheng ZQ, Esmailizadeh A, Hirimuthugoda NY, Ashari H, Suladari S, Zein MSA, Kusza S, Sohrabi S, et al.
Cell Research, Springer Nature [Academic Journals on Nature.Com] vol. 30 (8), 693-701.
01-08-2020
Arctic-adapted dogs emerged at the Pleistocene-Holocene transitionSinding MHS, Gopalakrishnan S, Ramos-Madrigal J, de Manuel M, Pitulko VV, Kuderna L, Feuerborn TR, Frantz LAF, Vieira FG, Niemann J, Samaniego Castruita JA, Carøe C, Andersen-Ranberg EU, Jordan PD, Pavlova EY, Nikolskiy PA, Kasparov AK, Ivanova VV, Willerslev E, Skoglund P, et al.
Science, Aaas vol. 368 (6498), 1495-1499.
26-06-2020
A mitochondrial genetic divergence proxy predicts the reproductive compatibility of mammalian hybridsAllen R, Ryan H, Davis BW, King C, Frantz L, Irving-Pease E, Barnett R, Linderholm A, Loog L, Haile J, Lebrasseur O, White M, Kitchener AC, Murphy WJ and Larson G
Proceedings of The Royal Society B: Biological Sciences, Royal Society, The vol. 287 (1928), 20200690-20200690.
03-06-2020
Animal domestication in the era of ancient genomicsFrantz LAF, Bradley DG, Larson G and Orlando L
Nature Reviews Genetics, Nature Research (Part of Springer Nature) vol. 21 (8), 449-460.
07-04-2020
Evidence of pathogen-induced immunogenetic selection across the large geographic range of a wild seabird.Levy H, Fiddaman SR, Vianna JA, Noll D, Clucas GV, Sidhu JKH, Polito MJ, Bost CA, Phillips RA, Crofts S, Miller GD, Pistorius P, Bonnadonna F, Bohec CL, Barbosa AA, Trathan P, Rey AR, Frantz LAF, Hart T and Smith AL
Molecular Biology and Evolution, Oxford University Press (OUP)
25-02-2020
Ancient DNA suggests modern wolves trace their origin to a Late Pleistocene expansion from BeringiaLoog L, Thalmann O, Sinding MHS, Schuenemann VJ, Perri A, Germonpré M, Bocherens H, Witt KE, Samaniego Castruita JA, Velasco MS, Lundstrøm IKC, Wales N, Sonet G, Frantz L, Schroeder H, Budd J, Jimenez EL, Fedorov S, Gasparyan B, Kandel AW, et al.
Molecular Ecology, Wiley vol. 29 (9), 1596-1610.
02-01-2020
Genomic consequences of population decline in critically endangered pangolins and their demographic historiesHu JY, Hao ZQ, Frantz L, Wu SF, Chen W, Jiang YF, Wu H, Kuang WM, Li H, Zhang YP and Yu L
National Science Review vol. 7 (4), 798-814.
01-01-2020
2019
Specialized sledge dogs accompanied Inuit dispersal across the North American ArcticAmeen C, Feuerborn TR, Brown SK, Linderholm A, Hulme-Beaman A, Lebrasseur O, Sinding MHS, Lounsberry ZT, Lin AT, Appelt M, Bachmann L, Betts M, Britton K, Darwent J, Dietz R, Fredholm M, Gopalakrishnan S, Goriunova OI, Grønnow B, Haile J, et al.
Proceedings of The Royal Society B: Biological Sciences, Royal Society, The vol. 286 (1916)
27-11-2019
Ancient pigs reveal a near-complete genomic turnover following their introduction to EuropeFrantz LAF, Haile J, Lin AT, Scheu A, Geörg C, Benecke N, Alexander M, Linderholm A, Mullin VE, Daly KG, Battista VM, Price M, Gron KJ, Alexandri P, Arbogast RM, Arbuckle B, Bǎlǎşescu A, Barnett R, Bartosiewicz L, Baryshnikov G, et al.
Proceedings of The National Academy of Sciences of The United States of America, National Academy of Sciences vol. 116 (35), 17231-17238.
27-08-2019
Microbial differences between dental plaque and historic dental calculus are related to oral biofilm maturation stageVelsko IM, Fellows Yates JA, Aron F, Hagan RW, Frantz LAF, Loe L, Martinez JBR, Chaves E, Gosden C, Larson G and Warinner C
Microbiome, Springer Nature vol. 7 (1)
06-07-2019
Genomic analysis on pygmy hog reveals extensive interbreeding during wild boar expansionLiu L, Bosse M, Megens H-J, Frantz LAF, Lee Y-L, Irving-Pease EK, Narayan G, Groenen MAM and Madsen O
Nature Communications, Springer Nature vol. 10 (1)
30-04-2019
Dog10K: An international sequencing effort to advance studies of canine domestication, phenotypes and healthOstrander EA, Wang GD, Larson G, Vonholdt BM, Davis BW, Jagannathan V, Hitte C, Wayne RK, Zhang YP, André C, Axelsson E, Boyko A, Forman O, Frantz L, Karlsson E, Kidd J, Leeb T, Lindblad-Toh K, Lohi H, Lohmueller KE, et al.
National Science Review, Oxford University Press (OUP) vol. 6 (4), 810-824.
10-04-2019
The Origin and Population History of the Endangered Golden Snub-Nosed Monkey (Rhinopithecus roxellana)Kuang WM, Ming C, Li HP, Wu H, Frantz L, Roos C, Zhang YP, Zhang CL, Jia T, Yang JY and Yu L
Molecular Biology and Evolution vol. 36 (3), 487-499.
01-03-2019
2018
Dogs accompanied humans during the Neolithic expansion into EuropeOllivier M, Tresset A, Frantz LAF, Bréhard S, Bălăşescu A, Mashkour M, Boroneant A, Pionnier-Capitan M, Lebrasseur O, Arbogast RM, Bartosiewicz L, Debue K, Rabinovich R, Sablin MV, Larson G, Hänni C, Hitte C and Vigne JD
Biology Letters, Royal Society, The vol. 14 (10)
17-10-2018
ABLE: blockwise site frequency spectra for inferring complex population histories and recombinationBeeravolu CR, Hickerson MJ, Frantz LAF and Lohse K
Genome Biology, Springer Nature vol. 19 (1)
25-09-2018
Selection of Appropriate Metagenome Taxonomic Classifiers for Ancient Microbiome ResearchVelsko IM, Frantz LAF, Herbig A, Larson G and Warinner C
Msystems, American Society For Microbiology vol. 3 (4), 10.1128/msystems.000-10.1128/msystems.000.
17-07-2018
A genetic perspective on the domestication continuumFRANTZ LAF and LARSON G
In Hybrid Communities: Biosocial Approaches to Domestication and Other Trans-Species Relationships, Taylor & Francis
30-05-2018
Synchronous diversification of Sulawesi's iconic artiodactyls driven by recent geological eventsFrantz LAF, Rudzinski A, Nugraha AMS, Evin A, Burton J, Hulme-Beaman A, Linderholm A, Barnett R, Vega R, Irving-Pease EK, Haile J, Allen R, Leus K, Shephard J, Hillyer M, Gillemot S, van den Hurk J, Ogle S, Atofanei C, Thomas MG, et al.
Proceedings of The Royal Society B, The Royal Society vol. 285 (1876)
11-04-2018
Rabbits and the Specious Origins of Domestication.Irving-Pease EK, Frantz LAF, Sykes N, Callou C and Larson G
Trends Ecol Evol vol. 33 (3), 149-152.
14-02-2018
2017
The dental calculus metabolome in modern and historic samples.Velsko IM, Overmyer KA, Speller C, Klaus L, Collins MJ, Loe L, Frantz LAF, Sankaranarayanan K, Lewis CM, Martinez JBR, Chaves E, Coon JJ, Larson G and Warinner C
Metabolomics vol. 13 (11), 134-134.
03-10-2017
Reconstructing Asian faunal introductions to eastern Africa from multi-proxy biomolecular and archaeological datasetsPrendergast ME, Buckley M, Crowther A, Frantz L, Eager H, Lebrasseur O, Hutterer R, Hulme-Beaman A, Van Neer W, Douka K, Veall M-A, Quintana Morales EM, Schuenemann VJ, Reiter E, Allen R, Dimopoulos EA, Helm RM, Shipton C, Mwebi O, Denys C, et al.
Plos One vol. 12 (8), e0182565-e0182565. Editors: Hoon Shin D.
17-08-2017
Analysis of the genetic variation in mitochondrial DNA, Y-chromosome sequences, and MC1R sheds light on the ancestry of Nigerian indigenous pigs.Adeola AC, Oluwole OO, Oladele BM, Olorungbounmi TO, Boladuro B, Olaogun SC, Nneji LM, Sanke OJ, Dawuda PM, Omitogun OG, Frantz L, Murphy RW, Xie H-B, Peng M-S and Zhang Y-P
Genet Sel Evol vol. 49 (1), 52-52.
26-06-2017
2016
A novel MC1R allele for black coat colour reveals the Polynesian ancestry and hybridization patterns of Hawaiian feral pigsLinderholm A, Spencer D, Battista V, Frantz L, Barnett R, Fleischer RC, James HF, Duffy D, Sparks JP, Clements DR, Andersson L, Dobney K, Leonard JA and Larson G
Royal Society Open Science vol. 3 (9), 160304-160304.
01-09-2016
Genomic and archaeological evidence suggest a dual origin of domestic dogs.Frantz LAF, Mullin VE, Pionnier-Capitan M, Lebrasseur O, Ollivier M, Perri A, Linderholm A, Mattiangeli V, Teasdale MD, Dimopoulos EA, Tresset A, Duffraisse M, McCormick F, Bartosiewicz L, Gál E, Nyerges ÉA, Sablin MV, Bréhard S, Mashkour M, Bălăşescu A, et al.
Science vol. 352 (6290), 1228-1231.
03-06-2016
2015
Artificial selection on introduced Asian haplotypes shaped the genetic architecture in European commercial pigsBosse M, Lopes MS, Madsen O, Megens H-J, Crooijmans RPMA, Frantz LAF, Harlizius B, Bastiaansen JWM and Groenen MAM
Proceedings of The Royal Society B, The Royal Society vol. 282 (1821)
22-12-2015
The Evolution of SuidaeFrantz L, Meijaard E, Gongora J, Haile J, Groenen MAM and Larson G
Annual Review of Animal Biosciences, Annual Reviews vol. 4 (1), 1-25.
02-11-2015
Inferring Bottlenecks from Genome-Wide Samples of Short Sequence BlocksBunnefeld L, Frantz LAF and Lohse K
Genetics, Oxford University Press (OUP) vol. 201 (3), 1157-1169.
03-09-2015
Evidence of long-term gene flow and selection during domestication from analyses of Eurasian wild and domestic pig genomesFrantz LAF, Schraiber JG, Madsen O, Megens H-J, Cagan A, Bosse M, Paudel Y, Crooijmans RPMA, Larson G and Groenen MAM
Nature Genetics, Springer Nature vol. 47 (10), 1141-1148.
31-08-2015
Copy number variation in the speciation of pigs: a possible prominent role for olfactory receptorsPaudel Y, Madsen O, Megens H-J, Frantz LAF, Bosse M, Crooijmans RPMA and Groenen MAM
Bmc Genomics, Springer Nature vol. 16 (1)
22-04-2015
Evolution of Tibetan wild boarsFrantz LAF, Madsen O, Megens H-J, Schraiber JG, Paudel Y, Bosse M, Crooijmans RPMA, Larson G and Groenen MAM
Nature Genetics, Springer Nature vol. 47 (3), 188-189.
25-02-2015
Hybrid origin of European commercial pigs examined by an in-depth haplotype analysis on chromosome 1Bosse M, Madsen O, Megens H-J, Frantz LAF, Paudel Y, Crooijmans RPMA and Groenen MAM
Frontiers in Genetics, Frontiers vol. 5
05-01-2015
2014
Testing models of speciation from genome sequences: divergence and asymmetric admixture in Island South‐East Asian Sus species during the Plio‐Pleistocene climatic fluctuationsFrantz LAF, Madsen O, Megens H, Groenen MAM and Lohse K
Molecular Ecology, Wiley vol. 23 (22), 5566-5574.
01-11-2014
Genomic analysis reveals selection for Asian genes in European pigs following human-mediated introgressionBosse M, Megens H-J, Frantz LAF, Madsen O, Larson G, Paudel Y, Duijvesteijn N, Harlizius B, Hagemeijer Y, Crooijmans RPMA and Groenen MAM
Nature Communications, Springer Nature vol. 5 (1)
15-07-2014
Untangling the hybrid nature of modern pig genomes: a mosaic derived from biogeographically distinct and highly divergent Sus scrofa populationsBosse M, Megens H, Madsen O, Frantz LAF, Paudel Y, Crooijmans RPMA and Groenen MAM
Molecular Ecology, Wiley vol. 23 (16), 4089-4102.
16-06-2014
The genetics of indirect ecological effects—plant parasites and aphid herbivoresRowntree JK, Zytynska SE, Frantz L, Hurst B, Johnson A and Preziosi RF
Frontiers in Genetics, Frontiers vol. 5
08-04-2014
Neandertal Admixture in Eurasia Confirmed by Maximum-Likelihood Analysis of Three GenomesLohse K and Frantz LAF
Genetics, Oxford University Press (OUP) vol. 196 (4), 1241-1251.
01-04-2014
2013
Host‐plant genotypic diversity and community genetic interactions mediate aphid spatial distributionZytynska SE, Frantz L, Hurst B, Johnson A, Preziosi RF and Rowntree JK
Ecology and Evolution, Wiley vol. 4 (2), 121-131.
15-12-2013
Genome sequencing reveals fine scale diversification and reticulation history during speciation in SusFrantz LA, Schraiber JG, Madsen O, Megens H-J, Bosse M, Paudel Y, Semiadi G, Meijaard E, Li N, Crooijmans RP, Archibald AL, Slatkin M, Schook LB, Larson G and Groenen MA
Genome Biology, Springer Nature vol. 14 (9)
01-01-2013
Evolutionary dynamics of copy number variation in pig genomes in the context of adaptation and domesticationPaudel Y, Madsen O, Megens H-J, Frantz LA, Bosse M, Bastiaansen JW, Crooijmans RP and Groenen MA
Bmc Genomics, Springer Nature vol. 14 (1)
01-01-2013
2012
Pig Domestication and Human-Mediated Dispersal in Western Eurasia Revealed through Ancient DNA and Geometric MorphometricsOttoni C, Flink LG, Evin A, Geörg C, De Cupere B, Van Neer W, Bartosiewicz L, Linderholm A, Barnett R, Peters J, Decorte R, Waelkens M, Vanderheyden N, Ricaut F-X, Çakırlar C, Çevik Ö, Hoelzel AR, Mashkour M, Karimlu AFM, Seno SS, et al.
Molecular Biology and Evolution, Oxford University Press (OUP) vol. 30 (4), 824-832.
22-11-2012
A high density recombination map of the pig reveals a correlation between sex-specific recombination and GC contentTortereau F, Servin B, Frantz L, Megens H-J, Milan D, Rohrer G, Wiedmann R, Beever J, Archibald AL, Schook LB and Groenen MA
Bmc Genomics, Springer Nature vol. 13 (1)
15-11-2012
Analyses of pig genomes provide insight into porcine demography and evolutionGroenen MAM, Archibald AL, Uenishi H, Tuggle CK, Takeuchi Y, Rothschild MF, Rogel-Gaillard C, Park C, Milan D, Megens H-J, Li S, Larkin DM, Kim H, Frantz LAF, Caccamo M, Ahn H, Aken BL, Anselmo A, Anthon C, Auvil L, et al.
Nature, Springer Nature vol. 491 (7424), 393-398.
14-11-2012
Regions of Homozygosity in the Porcine Genome: Consequence of Demography and the Recombination LandscapeBosse M, Megens H-J, Madsen O, Paudel Y, Frantz LAF, Schook LB, Crooijmans RPMA and Groenen MAM
Plos Genetics, Public Library of Science (Plos) vol. 8 (11)
01-01-2012
Grants
Grants of specific relevance to the Centre for Evolutionary and Functional GenomicsAfrican cattle genomics - SilverStreet CapitalLaurent Frantz
£95,000 SilverStreet Capital LLP
01-01-2021 - 31-12-2023
Linking livestock genetic diversity with three thousands years of agricultural crises and resilienceLaurent Frantz
£731,804 EU Commission - Horizon 2020
01-04-2020 - 31-03-2025
Biodiversity, environmental change and land-use policy in Sulawesi and MalukuStephen Rossiter and Laurent Frantz
£196,494 Natural Environment Research Council
15-11-2018 - 31-03-2022
The Consequences of Gene Flow between Wild and Domestic Populations during Livestock EvolutionLaurent Frantz
£190,197 NERC Natural Environment Research Council
01-10-2018 - 31-12-2022