Prof Himadri Gupta
Professor of Bioengineering and Biophysics
Director of Graduate Studies (SEMS)
School of Engineering and Materials Science
Queen Mary University of London
Queen Mary University of London
Research
Multimodal X-ray imaging, Nano- and micro biomechanics, Extracellular matrix, Collagen structure, Small-angle X-ray scattering and diffraction, Synchrotron technique development
Interests
HG is a bioengineer pioneering the analysis of nanoscale biophysics in the ECM of musculoskeletal tissues, by developing high-brilliance synchrotron X-ray nanomechanical imaging methods. His research has quantified the fundamental hierarchical deformation processes in bone at the Angstrom-micron level, uncovered ultrastructural mechanisms for fragility in osteoporosis models, and developed novel X-ray reconstruction models for complex biological tissues (ORCiD 0000-0003-2201-8933). More recently, his BBSRC (BB/R003610/1) funded research has focused on the mechanics of ageing collagen in cartilage, and he leads an EPSRC consortium (EP/V011235/1) to develop and disseminate TomoSAXS, a novel 3D molecular-to-macro scale biomechanical imaging technology for musculoskeletal tissues.Publications
Publications of specific relevance to the Centre for Bioengineering2024
Badar W, Inamdar SR, Fratzl P, Snow T, Terrill NJ, Knight MM and Gupta HS (2024). Nonlinear Stress‐Induced Transformations in Collagen Fibrillar Organization, Disorder and Strain Mechanisms in the Bone‐Cartilage Unit. Advanced Science, Wiley 11-11-2024
Chen Y, Wang K, Li X, Huang J, Gupta HS, Rui Y and Forster L (2024). Impact of SWCNTs and CMCS on efficacy of anastomosis and optical properties in vivo during laser biological tissue soldering. Optics & Laser Technology, Elsevier vol. 176 01-09-2024
Zhao X, Dong Z, Zhang C, Gupta H, Wu Z, Hua W, Zhang J, Huang P, Dong Y and Zhang Y (2024). A step towards 6D WAXD tensor tomography. IUCrJ, International Union of Crystallography (IUCr) vol. 11 (Pt 4), 502-509. 09-05-2024
Chen Y, Forster L, Wang K, Gupta HS, Li X, Huang J and Rui Y (2024). Investigation of collagen reconstruction mechanism in skin wound through dual-beam laser welding: Insights from multi-spectroscopy, molecular dynamics simulation, and finite element multiphysics simulation. Journal of Photochemistry and Photobiology B Biology, Elsevier vol. 255 26-04-2024
Chen Y, Chen M, Wang K, Huang J, Gupta HS, He K and Rui Y (2024). Accelerating the remodeling of collagen in cutaneous full‐thickness wound using FIR soldering technology with bio‐targeting nanocomposites hydrogel. Journal of Biophotonics, Wiley vol. 17 (5) 08-02-2024
2023
Barbieri E and Gupta HS (2023). Is Stress Relaxation in Sea Cucumber Dermis Chemoelastic? Marine Drugs, MDPI vol. 21 (12) 25-11-2023
Ahmed A, Kirk T, Forster L, O’Toole E, Gupta H and Rognoni E (2023). P08 Dissection of the molecular and cellular heterogeneity of dermal fibroblasts in skin fibrosis. British Journal of Dermatology, Oxford University Press (OUP) vol. 189 (1), e17-e17. 07-07-2023
Ahmed A, Kirk T, Forster L, O'Toole E, Gupta H and Rognoni E (2023). 1458 Dissection of the molecular and cellular heterogeneity of dermal fibroblasts in skin fibrosis. Journal of Investigative Dermatology, Elsevier vol. 143 (5) 01-05-2023
Sun M, Dong Z, Wu L, Yao H, Niu W, Xu D, Chen P, Gupta HS, Zhang Y, Dong Y, Chen C and Zhao L (2023). Fast extraction of three-dimensional nanofiber orientation from WAXD patterns using machine learning. IUCrJ, International Union of Crystallography (IUCr) vol. 10 (Pt 3), 297-308. 25-03-2023
Ahmed A, Kirk T, Forster L, O'Toole E, Gupta H and Rognoni E (2023). Dissection of the molecular and cellular heterogeneity of dermal fibroblasts in skin fibrosis. 01-01-2023
2022
Badar W, Ali H, Brooker ON, Newham E, Snow T, Terrill NJ, Tozzi G, Fratzl P, Knight MM and Gupta HS (2022). Collagen pre-strain discontinuity at the bone—Cartilage interface. PLOS ONE, Public Library of Science (PLoS) vol. 17 (9) 15-09-2022
Barbieri E, Mo J and Gupta HS (2022). Chemoviscoelasticity of the interfibrillar matrix of the dermis of the black sea cucumber Holuthuria atria. Mechanics of Materials, Elsevier vol. 168 01-05-2022
Dong Z, Chen S, Gupta HS, Zhao X, Yang Y, Chang G, Xue J, Zhang Y, Luo S and Dong Y (2022). In situ determination of the extreme damage resistance behavior in stomatopod dactyl club. Journal of Synchrotron Radiation, International Union of Crystallography (IUCr) vol. 29 (3), 775-786. 14-03-2022
Zhang Y, Hollis D, Ross R, Snow T, Terrill NJ, Lu Y, Wang W, Connelly J, Tozzi G and Gupta HS (2022). Investigating the Fibrillar Ultrastructure and Mechanics in Keloid Scars Using In Situ Synchrotron X-ray Nanomechanical Imaging. Materials (Basel), MDPI vol. 15 (5) 01-03-2022
Schöberl T and Gupta HS (2022). Effect of interphase boundaries on nanoindentation experiments on a Ni-base alloy. International Journal of Materials Research (formerly Zeitschrift fuer Metallkunde) vol. 94 (7), 813-818. 25-01-2022
2021
Weinkamer R, Gupta H, Lebowitz JL and Fratzl P (2021). Precipitate Size Distribution in Alloys with and without Lattice Misfit. INTERNATIONAL JOURNAL OF MATERIALS RESEARCH vol. 92 (1), 9-13. 21-12-2021
Inamdar SR, Prévost S, Terrill NJ, Knight MM and Gupta HS (2021). Reversible changes in the 3D collagen fibril architecture during cyclic loading of healthy and degraded cartilage. Acta Biomaterialia, Elsevier vol. 136, 314-326. 24-11-2021
Elphick M (2021). The Mutable Collagenous Tissue of Echinoderms: From Biology to Biomedical Applications. Soft Matter for Biomedical Applications, Royal Society of Chemistry 11-06-2021
Xi L, Barbieri E, Wang P, Wu W and Gupta H (2021). Separating effects of bone-quality changes at multiple scales in steroid-induced osteoporosis: Combining multiscale experimental and modelling approaches. Mechanics of Materials, Elsevier vol. 157 01-06-2021
De Falco P, Weinkamer R, Wagermaier W, Li C, Snow T, Terrill NJ, Gupta HS, Goyal P, Stoll M, Benner P and Fratzl P (2021). Tomographic X‐ray scattering based on invariant reconstruction: analysis of the 3D nanostructure of bovine bone. Journal of Applied Crystallography, International Union of Crystallography (IUCr) vol. 54 (2), 486-497. 03-03-2021
Fu S, Meng H, Inamdar S, Das B, Gupta H, Wang W, Thompson C and Knight M (2021). Activation of TRPV4 by mechanical, osmotic or pharmaceutical stimulation is anti-inflammatory blocking IL-1β mediated articular cartilage matrix destruction., Editors: Block JA. Osteoarthritis and Cartilage, Elsevier 01-01-2021
Gupta HS, Barbieri E, Inamdar SR and Mo J (2021). Chapter 2 Synchrotron X-ray Imaging Combined with Multiscale Modeling Applied to Biological Soft Tissues. Soft Matter for Biomedical Applications 34-60. 01-01-2021
2020
Zhang Y, Garrevoet J, Wang Y, Roeh JT, Terrill NJ, Falkenberg G, Dong Y and Gupta HS (2020). Molecular to Macroscale Energy Absorption Mechanisms in Biological Body Armour Illuminated by Scanning X-ray Diffraction with In Situ Compression. ACS Nano, American Chemical Society 09-10-2020
Xi L, Zhang Y, Gupta H, Terrill N, Wang P, Zhao T and Fang D (2020). A multiscale study of structural and compositional changes in a natural nanocomposite: Osteoporotic bone with chronic endogenous steroid excess. Bone, Elsevier vol. 143 29-09-2020
2019
Xi L, De Falco P, Barbieri E, Karunaratne A, Bentley L, Esapa CT, Davis GR, Terrill NJ, Cox RD, Pugno NM, Thakker RV, Weinkamer R, Wu WW, Fang DN and Gupta HS (2019). Reduction of fibrillar strain-rate sensitivity in steroid-induced osteoporosis linked to changes in mineralized fibrillar nanostructure. Bone, Elsevier vol. 131 11-11-2019
Wang Y, Zhang Y, Terrill NJ, Barbieri E, Pugno NM and Gupta HS (2019). Matrix-induced pre-strain and mineralization-dependent interfibrillar shear transfer enable 3D fibrillar deformation in a biogenic armour. Acta Biomaterialia, Elsevier 26-09-2019
Inamdar SR, Barbieri E, Terrill NJ, Knight MM and Gupta HS (2019). Proteoglycan degradation mimics static compression by altering the natural gradients in fibrillar organisation in cartilage. Acta Biomaterialia, Elsevier vol. 97, 437-450. 30-07-2019
2018
(2018). In Situ Mechanical Behavior of Regenerating Rat Calvaria Bones Under Tensile Load via Synchrotron Diffraction Characterization. Residual Stresses 2018. 11-09-2018
Kundanati L, Signetti S, Gupta HS, Menegon M and Pugno NM (2018). Multilayer stag beetle elytra perform better under external loading via non-symmetric bending properties. J R Soc Interface vol. 15 (144) 25-07-2018
Xi L, De Falco P, Barbieri E, Karunaratne A, Bentley L, Esapa CT, Terrill NJ, Brown SDM, Cox RD, Davis GR, Pugno NM, Thakker RV and Gupta HS (2018). Bone matrix development in steroid-induced osteoporosis is associated with a consistently reduced fibrillar stiffness linked to altered bone mineral quality. Acta Biomaterialia, Elsevier vol. 76, 295-307. 15-06-2018
Gupta HS, Szulgit G, Elphick MR and Mo J (2018). Unlocking the secrets of mutable collagenous tissue. Biochemist vol. 40 (1), 8-11. 01-02-2018
2017
Inamdar SR, Knight DP, Terrill NJ, Karunaratne A, Cacho-Nerin F, Knight MM and Gupta HS (2017). The Secret Life of Collagen: Temporal Changes in Nanoscale Fibrillar Pre-Strain and Molecular Organization During Physiological Loading of Cartilage. ACS Nano 11-08-2017
Zhang Y, De Falco P, Wang Y, Barbieri E, Paris O, Terrill NJ, Falkenberg G, Pugno NM and Gupta HS (2017). Towards in situ determination of 3D strain and reorientation in the interpenetrating nanofibre networks of cuticle. Nanoscale 19-07-2017
Blowes LM, Egertova M, Liu Y, Davis GR, Terrill NJ, Gupta HS and ELPHICK MR (2017). Body wall structure in the starfish Asterias rubens. Journal of Anatomy, Wiley 16-07-2017
De Falco P, Barbieri E, Pugno N and Gupta HS (2017). Staggered Fibrils and Damageable Interfaces Lead Concurrently and Independently to Hysteretic Energy Absorption and Inhomogeneous Strain Fields in Cyclically Loaded Antler Bone. ACS Biomaterials Science & Engineering 12-01-2017
2016
Gupta HS and Screen HRC (2016). Structural Building Blocks of Soft Tissues: Tendons and Heart Valves. Material Parameter Identification and Inverse Problems in Soft Tissue Biomechanics 1-35. 13-10-2016
Mo J, Prévost SF, Blowes LM, Egertová M, Terrill NJ, Wang W, Elphick MR and Gupta HS (2016). Interfibrillar stiffening of echinoderm mutable collagenous tissue demonstrated at the nanoscale. Proc Natl Acad Sci U S A 05-10-2016
Zhang Y, Paris O, Terrill NJ and Gupta HS (2016). Uncovering three-dimensional gradients in fibrillar orientation in an impact-resistant biological armour. Scientific Reports, Nature Publishing Group: Open Access Journals - Option C vol. 6, 26249-26249. 23-05-2016
2015
Karunaratne A, Xi L, Bentley L, Sykes D, Boyde A, Esapa CT, Terrill NJ, Brown SDM, Cox RD, Thakker RV and Gupta HS (2015). Multiscale alterations in bone matrix quality increased fragility in steroid induced osteoporosis. Bone, Elsevier vol. 84, 15-24. 02-12-2015
Patel IF, Kiryukhin MV, Yakovlev NL, Gupta HS and Sukhorukov GB (2015). Naturally inspired polyelectrolyte multilayer composite films synthesised through layer-by-layer assembly and chemically infiltrated with CaCO 3. Journal of Materials Chemistry B, Royal Society of Chemistry (RSC) vol. 3 (24), 4821-4830. 01-01-2015
2014
Guerette PA, Z. Tay G, Hoon S, Loke JJ, Hermawan AF, Schmitt CNZ, Harrington MJ, Masic A, Karunaratne A, Gupta HS, Tan KS, Schwaighofer A, Nowak C and Miserez A (2014). Integrative and comparative analysis of coiled-coil based marine snail egg cases - A model for biomimetic elastomers. Biomaterials Science vol. 2 (5), 710-722. 01-01-2014
Karunaratne A, Bentley L, Cox R, Boyde A, Esapa CT, Terrill NJ, Davis GR, Brown SDM, Thakker RV and Gupta HS (2014). Synchrotron Nano-Mechanical Imaging Techniques to Understand How Altered Bone Quality Increases Fracture Risk in Secondary Osteoporosis. 01-01-2014
2013
Hang F, Gupta HS and BARBER AH (2013). Nanointerfacial strength between non-collagenous protein and collagen fibrils in antler bone. Journal of the Royal Society Interface, Royal Society Publishing vol. 11 (92) 18-12-2013
Gupta HS, Krauss S, Kerschnitzki M, Karunaratne A, Dunlop JWC, Barber AH, Boesecke P, Funari SS and Fratzl P (2013). Intrafibrillar plasticity through mineral/collagen sliding is the dominant mechanism for the extreme toughness of antler bone. Journal of the Mechanical Behavior of Biomedical Materials vol. 28, 366-382. 01-12-2013
Karunaratne A, Boyde A, Esapa CT, Hiller J, Terrill NJ, Brown SDM, Cox RD, Thakker RV and Gupta HS (2013). Symmetrically reduced stiffness and increased extensibility in compression and tension at the mineralized fibrillar level in rachitic bone. Bone vol. 52 (2), 689-698. 01-02-2013
Karunaratne A, Terrill NJ and Gupta HS (2013). Synchrotron X-ray nanomechanical imaging of mineralized fiber composites. Methods Enzymol vol. 532, 415-473. 01-01-2013
Sukhorukov GB, Patel I, Sali C, Nzeako J, Zhang Y, Kiryukhin M, Terrill N, Barber AH and Gupta HS (2013). Naturally inspired mineralized ceramic/polyelectrolyte multilayer films assembled by physicochemical processes. 01-01-2013
2012
Harrington MJ, Wasko SS, Masic A, Fischer FD, Gupta HS and Fratzl P (2012). Pseudoelastic behaviour of a natural material is achieved via reversible changes in protein backbone conformation. Journal of the Royal Society Interface vol. 9 (76), 2911-2922. 07-11-2012
Karunaratne A, Davis GR, Hiller J, Esapa CT, Terrill NJ, Brown SDM, Cox RD, Thakker RV and Gupta HS (2012). Hypophosphatemic rickets is associated with disruption of mineral orientation at the nanoscale in the flat scapula bones of rachitic mice with development. Bone vol. 51 (3), 553-562. 01-09-2012
Stachewicz U, Hang F, Bailey RJ, Gupta HS, Frogley MD, Cinque G and Barber AH (2012). Recording IR spectra for individual electrospun fibers using an in situ AFM-synchrotron technique. Materials Research Society Symposium Proceedings vol. 1424, 19-23. 20-08-2012
Karunaratne A, Davis G, Hiller J, Esapa C, Terrill N, Brown S, Cox R, Thakker R and Gupta H (2012). DISRUPTION OF MUSCLE STRESS-MEDIATED MINERAL ORIENTATION AT THE NANOSCALE IN THE SCAPULAR BONES OF RICKETS MICE WITH DEVELOPMENT. Journal of Biomechanics, Elsevier vol. 45 01-07-2012
Anssari-Benam A, Gupta HS and Screen HRC (2012). Strain transfer through the aortic valve. Journal of Biomechanical Engineering vol. 134 (6) 29-06-2012
Karunaratne A, Esapa CR, Hiller J, Boyde A, Head R, Bassett JHD, Terrill NJ, Williams GR, Brown MA, Croucher PI, Brown SDM, Cox RD, Barber AH, Thakker RV and Gupta HS (2012). Significant deterioration in nanomechanical quality occurs through incomplete extrafibrillar mineralization in rachitic bone: Evidence from in-situ synchrotron X-ray scattering and backscattered electron imaging. Journal of Bone and Mineral Research vol. 27 (4), 876-890. 01-04-2012
Seto J, Busse B, Gupta HS, Schäfer C, Krauss S, Dunlop JWC, Masic A, Kerschnitzki M, Zaslansky P, Boesecke P, Catalá-Lehnen P, Schinke T, Fratzl P and Jahnen-Dechent W (2012). Accelerated growth plate mineralization and foreshortened proximal limb bones in fetuin-A knockout mice. PLoS One vol. 7 (10) 01-01-2012
Karunaratne A, Esapa C, Hiller J, Terril N, Brown S, Cox R, Thakker R and Gupta H (2012). Disruption in fibrillar level fracture mechanisms in rachitic mice bone: Measured using in-situ cantilever bending with microfocus saxd. 01-01-2012
Karunaratne A, Esapa C, Hiller J, Terrill N, Thakker R and Gupta H (2012). FUNCTIONAL LINK BETWEEN MATERIAL LEVEL STRUCTURAL ALTERATIONS IN STEROID INDUCED OSTEOPOROTIC BONE AND ITS INCREASED FRAGILITY. 01-01-2012
2011
Screen HRC, Seto J, Krauss S, Boesecke P and Gupta HS (2011). Extrafibrillar diffusion and intrafibrillar swelling at the nanoscale are associated with stress relaxation in the soft collagenous matrix tissue of tendons. Soft Matter vol. 7 (23), 11243-11251. 07-11-2011
Wang R and Gupta HS (2011). Deformation and fracture mechanisms of bone and nacre. Annual Review of Materials Research vol. 41, 41-73. 04-08-2011
Seidel R, Gourrier A, Kerschnitzki M, Burghammer M, Fratzl P, Gupta HS and Wagermaier W (2011). Synchrotron 3D SAXS analysis of bone nanostructure. Bioinspired, Biomimetic and Nanobiomaterials vol. 1, 123-131. 01-01-2011
2010
Gupta HS (2010). Nanoscale Deformation Mechanisms in Biological Tissues. Nanotechnologies for the Life Sciences 11-08-2010
Fratzl P, Gupta HS, Roschger P and Klaushofer K (2010). Bone Nanostructure and its Relevance for Mechanical Performance, Disease and Treatment. Nanotechnology 345-360. 15-07-2010
Blouin S, Paschalis E, Gupta H, Fratzl-Zelman N, Pischon N, Trackman PC, Mäki JM, Roschger P and Klaushofer K (2010). Bone material properties in lysyl oxidase knock-out mice. Bone, Elsevier vol. 47 01-06-2010
Gupta HS, Seto J, Krauss S, Boesecke P and Screen HRC (2010). In situ multi-level analysis of viscoelastic deformation mechanisms in tendon collagen. Journal of Structural Biology vol. 169 (2), 183-191. 01-02-2010
Gupta H, Fratzl P, Kerschnitzki M, Krauss S, Seto J, Wagermaier W, Benecke G, Boesecke P, Funari S, Currey J and Estevez J (2010). Mechanisms of Bone Deformation and Fracture. 01-01-2010
2009
Neira IS, Kolen'ko YV, Lebedev OI, Van Tendeloo G, Gupta HS, Matsushita N, Yoshimura M and Guitián F (2009). Rational synthesis of a nanocrystalline calcium phosphate cement exhibiting rapid conversion to hydroxyapatite. Materials Science and Engineering C vol. 29 (7), 2124-2132. 31-08-2009
Harrington MJ, Gupta HS, Fratzl P and Waite JH (2009). Collagen insulated from tensile damage by domains that unfold reversibly: In situ X-ray investigation of mechanical yield and damage repair in the mussel byssus. Journal of Structural Biology vol. 167 (1), 47-54. 01-07-2009
Krauss S, Fratzl P, Seto J, Currey JD, Estevez JA, Funari SS and Gupta HS (2009). Inhomogeneous fibril stretching in antler starts after macroscopic yielding: Indication for a nanoscale toughening mechanism. Bone vol. 44 (6), 1105-1110. 01-06-2009
Fratzl P, Gupta HS, Roschger P and Klaushofer K (2009). Nanomedicine. Nanomedicine , Editors: Vogel V, Schmid G, Krug H, Waser R and Fuchs H. 345-360. 11-05-2009
Benecke G, Kerschnitzki M, Fratzl P and Gupta HS (2009). Digital image correlation shows localized deformation bands in inelastic loading of fibrolamellar bone. Journal of Materials Research vol. 24 (2), 421-429. 01-02-2009
Gupta H, Krauss S, Seto J, Wagermaier W, Kerschnitzki M, Benecke G, Zaslansky P, Boesecke P, Funari SS, Kirchner HOK and Fratzl P (2009). Nanoscale deformation mechanisms in bone. BONE vol. 44, S33-S34. 01-01-2009
Neira IS, Kolen'ko YV, Lebedev OI, Van Tendeloo G, Gupta HS, Guitian F and Yoshimura M (2009). An Effective Morphology Control of Hydroxyapatite Crystals via Hydrothermal Synthesis. CRYST GROWTH DES vol. 9 (1), 466-474. 01-01-2009
2008
Gupta HS and Zioupos P (2008). Fracture of bone tissue: The 'hows' and the 'whys'. Medical Engineering and Physics vol. 30 (10), 1209-1226. 01-12-2008
Seto J, Gupta HS, Zaslansky P, Wagner HD and Fratzl P (2008). Tough lessons from bone: Extreme mechanical anisotropy at the mesoscale. Advanced Functional Materials vol. 18 (13), 1905-1911. 09-07-2008
Gupta HS (2008). Collagen: Structure and Mechanics. Collagen , Editors: Fratzl P. 155-173. 30-05-2008
Gamsjager S, Kazanci M, Manjubala I, Gupta HS, Roschger P, Paschalis EP, Klaushofer K and Fratzl P (2008). Microstructure of cortical bone as studied by Raman spectroscopy (composition vs orientation). 01-01-2008
2007
Fratzl P, Gupta HS, Fischer FD and Kolednik O (2007). Hindered crack propagation in materials with periodically varying young's modulus - Lessons from biological materials. Advanced Materials vol. 19 (18), 2657-2661. 17-09-2007
Kazanci M, Wagner HD, Manjubala NI, Gupta HS, Paschalis E, Roschger P and Fratzl P (2007). Raman imaging of two orthogonal planes within cortical bone. Bone vol. 41 (3), 456-461. 01-09-2007
Gupta HS, Fratzl P, Kerschnitzki M, Benecke G, Wagermaier W and Kirchner HOK (2007). Evidence for an elementary process in bone plasticity with an activation enthalpy of 1 eV. Journal of the Royal Society Interface vol. 4 (13), 277-282. 22-04-2007
Gourrier A, Wagermaier W, Burghammer M, Lammie D, Gupta HS, Fratzl P, Riekel C, Wess TJ and Paris O (2007). Scanning X-ray imaging with small-angle scattering contrast. Journal of Applied Crystallography vol. 40 (SUPPL. 1) 01-04-2007
Fratzl P, Gupta H and Burgert I (2007). Mechanical functionality by hierarchical structuring — Lessons from biological materials. Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology, Elsevier vol. 146 (4) 01-04-2007
Wagermaier W, Gupta HS, Gourrier A, Paris O, Roschger P, Burghammer M, Riekel C and Fratzl P (2007). Scanning texture analysis of lamellar bone using microbeam synchrotron X-ray radiation. Journal of Applied Crystallography vol. 40 (1), 115-120. 12-01-2007
Gupta HS and Fratzl P (2007). Handbook of Biomineralization: . Biological aspects and structure formation. Handbook of Biomineralization: . Biological aspects and structure formation , Editors: Bäeuerlein E, Behrens P and Epple M. 397-414. 01-01-2007
2006
Gupta HS, Seto J, Wagermaier W, Zaslansky P, Boesecke P and Fratzl P (2006). Cooperative deformation of mineral and collagen in bone at the nanoscale. Proc Natl Acad Sci U S A vol. 103 (47), 17741-17746. 21-11-2006
Fratzl P, Roschger P, Gupta HS, Peterlik H, Paschalis EP and Klaushofer K (2006). Materials science basis of bone quality. 01-11-2006
Gupta HS, Stachewicz U, Wagermaier W, Roschger P, Wagner HD and Fratzl P (2006). Mechanical modulation at the lamellar level in osteonal bone. Journal of Materials Research vol. 21 (8), 1913-1921. 01-08-2006
Gupta HS, Wagermaier W, Zickler GA, Hartmann J, Funari SS, Roschger P, Wagner DH and Fratzl P (2006). Fibrillar level fracture in bone beyond the yield point. International Journal of Fracture vol. 139 (3-4), 425-436. 01-06-2006
Wagermaier W, Gupta HS, Gourrier A, Burghammer M, Roschger P and Fratzl P (2006). Spiral twisting of fiber orientation inside bone lamellae. BIOINTERPHASES vol. 1 (1), 1-5. 01-03-2006
2005
Gehrke N, Nassif N, Pinna N, Antonietti M, Gupta HS and Cölfen H (2005). Retrosynthesis of nacre via amorphous precursor particles. Chemistry of Materials vol. 17 (26), 6514-6516. 27-12-2005
Gupta HS, Wagermaier W, Zickler GA, Aroush DRB, Funari SS, Roschger P, Wagner HD and Fratzl P (2005). Nanoscale deformation mechanisms in bone. Nano Letters vol. 5 (10), 2108-2111. 01-10-2005
Wagermaier W, Gupta HS, Gourrier A, Roschger P, Burghammer M, Paris O, Riekel C and Fratzl P (2005). Scanning texture analysis of lamellar bone using microbeam synchrotron radiation. 23-08-2005
Paris O, Fratzl P, Gourrier A, Gupta H, Wagermaier W, Loidl D, Peterlik H, Burghammer M and Riekel C (2005). Microbeam diffraction of hierarchical nanocomposites. 23-08-2005
Fratzl P, Gupta HS, Wagermaier W, Roschger P, Gourrier A and Paris O (2005). Time- and position-resolved X-ray scattering of bone and cartilage. 23-08-2005
Fratzl P, Gupta HS, Paris O, Valenta A, Roschger P and Klaushofer K (2005). Diffracting stacks of cards - Some thoughts about small-angle scattering from bone. Progress in Colloid and Polymer Science vol. 130, 33-39. 29-07-2005
Manjubala I, Roschger P, Paschalis E, Zoehrer R, Gupta HS, Klaushofer K and Fratzl P (2005). Correlation of nanomechanical properties and bone organic/inorganic components in osteolathyritic treated rat bones. 01-06-2005
Gupta HS, Schratter S, Tesch W, Roschger P, Berzlanovich A, Schoeberl T, Klaushofer K and Fratzl P (2005). Two different correlations between nanoindentation modulus and mineral content in the bone-cartilage interface. Journal of Structural Biology vol. 149 (2), 138-148. 01-02-2005
2004
Fratzl P, Burgert I and Gupta HS (2004). On the role of interface polymers for the mechanics of natural polymeric composites. Physical Chemistry Chemical Physics vol. 6 (24), 5575-5579. 21-12-2004
Gindl W, Gupta HS, Schöberl T, Lichtenegger HC and Fratzl P (2004). Mechanical properties of spruce wood cell walls by nanoindentation. Applied Physics A: Materials Science and Processing vol. 79 (8), 2069-2073. 01-12-2004
Gupta HS, Messmer P, Roschger P, Bernstorff S, Klaushofer K and Fratzl P (2004). Synchrotron diffraction study of deformation mechanisms in mineralized tendon. Physical Review Letters vol. 93 (15) 08-10-2004
Fratzl P, Gupta HS, Paschalis EP and Roschger P (2004). Structure and mechanical quality of the collagen-mineral nano-composite in bone. Journal of Materials Chemistry vol. 14 (14), 2115-2123. 21-07-2004
Weinkamer R, Fratzl P, Gupta HS, Penrose O and Lebowitz JL (2004). Using kinetic Monte Carlo simulations to study phase separation in alloys. Phase Transitions vol. 77 (5-7), 433-456. 01-05-2004
2003
Schöberl T, Gupta HS and Fratzl P (2003). Measurements of mechanical properties in Ni-base superalloys using nanoindentation and atomic force microscopy. Materials Science and Engineering: A vol. 363 (1-2), 211-220. 20-12-2003
Roschger P, Gupta HS, Weber M, Valenta A, Misof BM, Schratter S, Jager I, Klaushofer K and Fratzl P (2003). Bone quality at material level as defined by concentration, size, shape, and alignment of mineral particles. 01-11-2003
Gupta HS, Roschger P, Zizak I, Fratzl-Zelman N, Nader A, Klaushofer K and Fratzl P (2003). Mineralized microstructure of calcified avian tendons: A scanning small angle X-ray scattering study. Calcified Tissue International vol. 72 (5), 567-576. 01-05-2003
Roschger P, Gupta HS, Berzlanovich A, Ittner G, Dempster DW, Fratzl P, Cosman F, Parisien M, Lindsay R, Nieves JW and Klaushofer K (2003). Constant mineralization density distribution in cancellous human bone. Bone vol. 32 (3), 316-323. 01-03-2003
Schöberl T and Gupta HS (2003). Effect of interphase boundaries on nanoindentation experiments on a Ni-base alloy. Zeitschrift fuer Metallkunde/Materials Research and Advanced Techniques vol. 94 (7), 813-818. 01-01-2003
2002
Gindl W, Gupta HS and Grunwald C (2002). Lignification of spruce tracheid secondary cell walls related to longitudinal hardness and modulus of elasticity using nano-indentation. CAN J BOT vol. 80 (10), 1029-1033. 01-10-2002
Paris O, Gupta H, Tesch W, Roschger P and Fratzl P (2002). Scanning-SAXS: a tool for structural characterization of complex materials at the micrometer and the nanometer scale. 06-08-2002
Gindl W and Gupta HS (2002). Cell-wall hardness and Young's modulus of melamine-modified spruce wood by nano-indentation. Composites Part A: Applied Science and Manufacturing vol. 33 (8), 1141-1145. 01-08-2002
2001
Weinkamer R, Gupta H, Lebowitz JL and Fratzl P (2001). Precipitate size distribution in alloys with and without lattice misfit. Zeitschrift fuer Metallkunde/Materials Research and Advanced Techniques vol. 92 (1), 9-13. 01-01-2001
Gupta H, Weinkamer R, Fratzl P and Lebowitz JL (2001). Microscopic computer simulations of directional coarsening in face-centered cubic alloys. Acta Materialia, Elsevier vol. 49 (1), 53-63. 01-01-2001
2000
Weinkamer R, Gupta H, Fratzl P and Lebowitz JL (2000). Dynamics of mesoscopic precipitate lattices in phase-separating alloys under external load. Europhysics Letters vol. 52 (2), 224-230. 01-01-2000
1996
Gupta HS and Ramaswamy R (1996). Backbones of traffic jams. Journal of Physics A: Mathematical and Theoretical, IOP Publishing vol. 29 (21) 07-11-1996
Grants
Grants of specific relevance to the Centre for BioengineeringTomo-SAXS: Imaging full-field molecular-to-macroscale biophysics of fibrous tissuesHimadri Gupta
£451,556 EPSRC Engineering and Physical Sciences Research Council (26-04-2021 - 25-10-2025)
Correlating structural and proteomic techniques on cartilageHimadri Gupta and Martin Knight
£18,515 MRC Medical Research Council (24-07-2022 - 28-02-2023)
Collagen Fibrillar Network in Ageing CartilageHimadri Gupta and Martin Knight
£374,874 BBSRC Biotechnology and Biological Sciences Research Council (01-10-2017 - 24-07-2023)