Dr Ann-Marie de Lange
Lecturer in Population Neuroscience & Applied Machine Learning
School of Biological and Behavioural Sciences
Queen Mary University of London
Queen Mary University of London
Research
Brain imaging (MRI), Population Health, Women's Health, Machine Learning
Publications
Publications of specific relevance to the Centre for Brain and Behaviour2025
Author Response: Sex-Dependent Effects of Cardiometabolic Health and APOE4 on Brain Age: A Longitudinal Cohort Study.Subramaniapillai S Cole JH de Lange A-MG
Neurology, Wolters Kluwer vol. 105 (9)
17-10-2025
Investigating Shared Cardiovascular Factors and Genetic Overlap of Pregnancy-Related Disorders, Major Depressive Disorder, and Alzheimer’s DiseaseBiological Psychiatry, Elsevier
01-10-2025
A Bayesian analysis of diagnostic timelines across Alzheimer's disease, frontotemporal dementia, and other neurodegenerative conditionsAlzheimer's & Dementia Diagnosis Assessment & Disease Monitoring, Wiley vol. 17 (3)
01-07-2025
Menopausal hormone therapy and the female brain: Leveraging neuroimaging and prescription registry data from the UK Biobank cohortElife, Elife vol. 13
29-05-2025
Mediation Analyses Link Cardiometabolic Factors and Liver Fat With White Matter Hyperintensities and Cognitive Performance: A UK Biobank StudyBiological Psychiatry Global Open Science, Elsevier vol. 5 (4)
20-03-2025
2024
Sex-Dependent Effects of Cardiometabolic Health and APOE4 on Brain AgeNeurology, Wolters Kluwer vol. 103 (6)
22-08-2024
Dimensions of Early-Life Adversity Are Differentially Associated With Patterns of Delayed and Accelerated Brain MaturationBiological Psychiatry, Elsevier vol. 97 (1), 64-72.
29-07-2024
Linking menopause-related factors, history of depression, APOE ε4, and proxies of biological aging in the UK biobank cohortHormones and Behavior, Elsevier vol. 164
29-06-2024
An evolutionary timeline of the oxytocin signaling pathwayCommunications Biology, Springer Nature vol. 7 (1)
17-04-2024
Dissecting unique and common variance across body and brain health indicators using age predictionHuman Brain Mapping, Wiley vol. 45 (6)
15-04-2024
Advancing the neuroscience of human pregnancyNature Neuroscience, Springer Nature vol. 27 (5), 805-807.
10-04-2024
Parental status and markers of brain and cellular age: A 3D convolutional network and classification studyPsychoneuroendocrinology, Elsevier vol. 165
02-04-2024
Investigating the synergistic effects of hormone replacement therapy, apolipoprotein E and age on brain health in the UK BiobankHuman Brain Mapping, Wiley vol. 45 (2)
01-02-2024
Brain asymmetries from mid- to late life and hemispheric brain ageNature Communications, Springer Nature vol. 15 (1)
01-02-2024
2023
Recommendations for a Better Understanding of Sex and Gender in the Neuroscience of Mental HealthBiological Psychiatry Global Open Science, Elsevier vol. 4 (2)
30-12-2023
Cardiometabolic health across menopausal years is linked to white matter hyperintensities up to a decade laterFrontiers in Global Women's Health, Frontiers vol. 4
21-12-2023
Sex and gender in health research: Intersectionality mattersFrontiers in Neuroendocrinology, Elsevier vol. 72
28-10-2023
Sex steroids and the female brain across the lifespan: insights into risk of depression and Alzheimer's diseaseThe Lancet Diabetes & Endocrinology, Elsevier vol. 11 (12), 926-941.
18-10-2023
Sex and gender in infection and immunity: addressing the bottlenecks from basic science to public health and clinical applicationsPasin C Consiglio CR Huisman JS de Lange A-MG Peckham H Vallejo-Yagüe E Abela IA Islander U et al.
Royal Society Open Science, The Royal Society vol. 10 (7)
01-07-2023
Development and validation of a dementia risk score in the UK Biobank and Whitehall II cohortsBmj Mental Health, Bmj vol. 26 (1)
01-07-2023
Bio-psycho-social factors’ associations with brain age: a large-scale UK Biobank diffusion study of 35,749 participantsFrontiers in Psychology, Frontiers vol. 14
09-06-2023
Brain‐wide associations between white matter and age highlight the role of fornix microstructure in brain ageingHuman Brain Mapping, Wiley vol. 44 (10), 4101-4119.
17-05-2023
Genetic architecture of brain age and its causal relations with brain and mental disordersMolecular Psychiatry, Springer Nature vol. 28 (7), 3111-3120.
10-05-2023
Topography of associations between cardiovascular risk factors and myelin loss in the ageing human brainCommunications Biology, Springer Nature vol. 6 (1)
10-04-2023
Linking brain maturation and puberty during early adolescence using longitudinal brain age prediction in the ABCD cohortDevelopmental Cognitive Neuroscience, Elsevier vol. 60
22-02-2023
Shared pattern of impaired social communication and cognitive ability in the youth brain across diagnostic boundariesDevelopmental Cognitive Neuroscience, Elsevier vol. 60
18-02-2023
Visual processing deficits in patients with schizophrenia spectrum and bipolar disorders and associations with psychotic symptoms, and intellectual abilitiesHeliyon, Elsevier vol. 9 (2)
01-02-2023
Associations between reproductive history, hormone use, APOE ε4 genotype and cognition in middle- to older-aged women from the UK BiobankFrontiers in Aging Neuroscience, Frontiers vol. 14
19-01-2023
2022
The link between liver fat and cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body compositionCommunications Biology, Springer Nature vol. 5 (1)
19-11-2022
Longitudinal brain age prediction and cognitive function after strokeNeurobiology of Aging, Elsevier vol. 122, 55-64.
29-10-2022
Cognitive and hippocampal changes weeks and years after memory trainingScientific Reports, Springer Nature vol. 12 (1)
12-05-2022
Sex‐ and age‐specific associations between cardiometabolic risk and white matter brain age in the UK Biobank cohortHuman Brain Mapping, Wiley vol. 43 (12), 3759-3774.
23-04-2022
Oxytocin receptor expression patterns in the human brain across developmentNeuropsychopharmacology, Springer Nature vol. 47 (8), 1550-1560.
28-03-2022
Mind the gap: Performance metric evaluation in brain‐age predictionHuman Brain Mapping, Wiley vol. 43 (10), 3113-3129.
21-03-2022
Adipose tissue distribution from body MRI is associated with cross-sectional and longitudinal brain age in adultsNeuroimage Clinical, Elsevier vol. 33
01-01-2022
Associations between abdominal adipose tissue, reproductive span, and brain characteristics in post-menopausal womenNeuroimage Clinical, Elsevier vol. 36
01-01-2022
2021
Brain age prediction using fMRI network coupling in youths and associations with psychiatric symptomsNeuroimage Clinical, Elsevier vol. 33
20-12-2021
Oxytocin-pathway polygenic scores for severe mental disorders and metabolic phenotypes in the UK BiobankTranslational Psychiatry, Springer Nature vol. 11 (1)
25-11-2021
Cardiometabolic risk factors associated with brain age and accelerated brain ageingHuman Brain Mapping, Wiley vol. 43 (2), 700-720.
09-10-2021
Prominent health problems, socioeconomic deprivation, and higher brain age in lonely and isolated individuals: A population-based studyBehavioural Brain Research, Elsevier vol. 414
04-08-2021
A history of previous childbirths is linked to women's white matter brain age in midlife and older ageHuman Brain Mapping, Wiley vol. 42 (13), 4372-4386.
12-06-2021
Fast qualitY conTrol meThod foR derIved diffUsion Metrics (YTTRIUM) in big data analysis: U.K. Biobank 18,608 exampleHuman Brain Mapping, Wiley vol. 42 (10), 3141-3155.
31-03-2021
Apolipoprotein ɛ4 Status and Brain Structure 12 Months after Mild Traumatic Injury: Brain Age Prediction Using Brain Morphometry and Diffusion Tensor ImagingJournal of Clinical Medicine, Mdpi vol. 10 (3)
22-01-2021
In Vivo Amygdala Nuclei Volumes in Schizophrenia and Bipolar DisordersSchizophrenia Bulletin, Oxford University Press (OUP) vol. 47 (5), 1431-1441.
22-01-2021
Linking objective measures of physical activity and capability with brain structure in healthy community dwelling older adultsNeuroimage Clinical, Elsevier vol. 31
01-01-2021
2020
The scientific body of knowledge: Whose body does it serve? A spotlight on women’s brain healthFrontiers in Neuroendocrinology, Elsevier vol. 60
28-12-2020
Multimodal imaging improves brain age prediction and reveals distinct abnormalities in patients with psychiatric and neurological disordersHuman Brain Mapping, Wiley vol. 42 (6), 1714-1726.
19-12-2020
Prediction of brain age and cognitive age: Quantifying brain and cognitive maintenance in agingHuman Brain Mapping, Wiley vol. 42 (6), 1626-1640.
14-12-2020
Within-session verbal learning slope is predictive of lifespan delayed recall, hippocampal volume, and memory training benefit, and is heritableScientific Reports, Springer Nature vol. 10 (1)
03-12-2020
White matter microstructure across the adult lifespan: A mixed longitudinal and cross-sectional study using advanced diffusion models and brain-age predictionNeuroimage, Elsevier vol. 224
09-10-2020
Women's brain aging: Effects of sex‐hormone exposure, pregnancies, and genetic risk for Alzheimer's diseaseHuman Brain Mapping, Wiley vol. 41 (18), 5141-5150.
28-08-2020
Multimodal brain-age prediction and cardiovascular risk: The Whitehall II MRI sub-studyNeuroimage, Elsevier vol. 222
21-08-2020
The maternal brain: Region‐specific patterns of brain aging are traceable decades after childbirthHuman Brain Mapping, Wiley vol. 41 (16), 4718-4729.
07-08-2020
Brain Age Prediction Reveals Aberrant Brain White Matter in Schizophrenia and Bipolar Disorder: A Multisample Diffusion Tensor Imaging StudyBiological Psychiatry Cognitive Neuroscience and Neuroimaging, Elsevier vol. 5 (12), 1095-1103.
08-07-2020
Towards an understanding of women’s brain aging: the immunology of pregnancy and menopauseFrontiers in Neuroendocrinology, Elsevier vol. 58
03-06-2020
Risk- and protective factors for memory plasticity in agingAging Neuropsychology and Cognition, Taylor & Francis vol. 28 (2), 201-217.
25-02-2020
Commentary: Correction procedures in brain-age predictionNeuroimage Clinical, Elsevier vol. 26
01-01-2020
2019
Self-reported Sleep Problems Related to Amyloid Deposition in Cortical Regions with High HOMER1 Gene ExpressionCerebral Cortex, Oxford University Press (OUP) vol. 30 (4), 2144-2156.
11-11-2019
Population-based neuroimaging reveals traces of childbirth in the maternal brainProceedings of The National Academy of Sciences of The United States of America, Proceedings of The National Academy of Sciences vol. 116 (44), 22341-22346.
15-10-2019
2018
Multimodal cortical and hippocampal prediction of episodic‐memory plasticity in young and older adultsHuman Brain Mapping, Wiley vol. 39 (11), 4480-4492.
13-07-2018
The Temporal Dynamics of Brain Plasticity in AgingCerebral Cortex, Oxford University Press (OUP) vol. 28 (5), 1857-1865.
27-02-2018
2017
The effects of memory training on behavioral and microstructural plasticity in young and older adultsHuman Brain Mapping, Wiley vol. 38 (11), 5666-5680.
07-08-2017
2016
White matter integrity as a marker for cognitive plasticity in agingNeurobiology of Aging, Elsevier vol. 47, 74-82.
15-07-2016
2015
Premises of plasticity — And the loneliness of the medial temporal lobeNeuroimage, Elsevier vol. 131, 48-54.
24-10-2015
Functional connectivity change across multiple cortical networks relates to episodic memory changes in agingNeurobiology of Aging, Elsevier vol. 36 (12), 3255-3268.
24-08-2015
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