Dr Roman Arguello
Senior Lecturer in Genetics, Genomics and Fundamental Cell Biology
Theme Lead for Genomics of Evolution and Development
School of Biological and Behavioural Sciences
Queen Mary University of London
Research
evolutionary genomics, sensory neurobiology, evo-devo, behaviour
Interests
Our lab uses evolutionary/population genomic and neurobiology approaches to investigate the genetic and cellular changes underlying the diversification of sensory systems. These aims link with related topics in evolutionary biology such as the roles that local adaptation, gene flow, and demographic histories play in shaping genetic and phenotypic changes.
Publications of specific relevance to the Centre for Evolutionary and Functional Genomics
Publications of specific relevance to the Centre for Evolutionary and Functional Genomics
2025
Evolution of temperature preference behaviour among Drosophila larvaeKafle T Grub M Sakagiannis P Nawrot MP Arguello JR
Iscience,
Elsevier vol. 28 (7)
31-05-20252024
Evolution of chemosensory tissues and cells across ecologically diverse DrosophilidsBontonou G Saint-Leandre B Kafle T Hassan A
Nature Communications,
Nature Research vol. 15 (1047)
05-02-2024 2023
Sensory neuron population expansion enhances odor tracking without sensitizing projection neuronsTakagi S Sancer G Abuin L Stupski SD Arguello JR Prieto-Godino LL Stern DL Cruchet S et al.
Nature Communications,
Nature Research vol. 4 (09-22), 2023.09.15.556782-2023.09.15.556782.
15-09-2023 2022
Copy number changes in co-expressed odorant receptor genes enable selection for sensory differences in drosophilid speciesAuer TO Álvarez-Ocaña R Cruchet S
Nature Ecology & Evolution,
Springer Nature vol. 6 (9), 1343-1353.
21-07-2022 2021
Targeted molecular profiling of rare olfactory sensory neurons identifies fate, wiring and functional determinantsArguello JR Abuin L Armida J Mika K Chai PC
Elife,
Elife vol. 10, e63036-e63036.
05-03-2021 2020
Olfactory receptor and circuit evolution promote host specializationAuer TO Khallaf MA Silbering AF Zappia G Ellis K Álvarez-Ocaña R Arguello JR Caron SJC
Nature,
Springer Nature vol. 579 (7799), 402-408.
04-03-2020 2019
Demographic History of the Human Commensal Drosophila melanogasterArguello JR Laurent S Clark AG
Genome Biology and Evolution,
Oxford University Press (OUP) vol. 11 (3), 844-854.
31-01-2019 2017
Open questions: Tackling Darwin’s “instincts”: the genetic basis of behavioral evolutionArguello JR Benton R
Bmc Biology,
Springer Nature vol. 15 (1)
03-04-2017 Survey of Global Genetic Diversity Within the Drosophila Immune SystemEarly AM Arguello JR Cardoso-Moreira M Gottipati S
Genetics,
Oxford University Press (OUP) vol. 205 (1), 353-366.
01-01-2017 2016
Olfactory receptor pseudo-pseudogenesPrieto-Godino LL Rytz R Bargeton B Abuin L Benton R
Nature,
Springer Nature vol. 539 (7627), 93-97.
24-10-2016 Extensive local adaptation within the chemosensory system following Drosophila melanogaster’s global expansionArguello JR Cardoso-Moreira M Grenier JK Clark AG
Nature Communications,
Springer Nature vol. 7 (1)
13-06-2016 Evidence for the fixation of gene duplications by positive selection in DrosophilaCardoso-Moreira M Arguello JR Gottipati S Grenier JK Clark AG
Genome Research,
Cold Spring Harbor Laboratory vol. 26 (6), 787-798.
12-04-2016 2015
Global Diversity Lines–A Five-Continent Reference Panel of Sequenced Drosophila melanogaster StrainsGrenier JK Arguello JR Moreira MC Gottipati S Hackett SR Boughton R
G3: Genes, Genomes, Genetics,
Oxford University Press (OUP) vol. 5 (4), 593-603.
01-04-2015 2012
Mutation spectrum of Drosophila CNVs revealed by breakpoint sequencingCardoso-Moreira M Arguello JR
Genome Biology,
Springer Nature vol. 13 (12)
01-01-2012 2011
Gene Duplication and Ectopic Gene Conversion in DrosophilaArguello JR Connallon T
Genes,
Mdpi vol. 2 (1), 131-151.
11-02-2011 2009
Recombination Yet Inefficient Selection along the Drosophila melanogaster Subgroup's Fourth ChromosomeArguello JR Zhang Y Kado T Fan C Innan H Wang W
Molecular Biology and Evolution,
Oxford University Press (OUP) vol. 27 (4), 848-861.
14-12-2009 2008
Repetitive Element-Mediated Recombination as a Mechanism for New Gene Origination in DrosophilaYang S Arguello JR Li X Ding Y Zhou Q Zhang Y Long M
Plos Genetics,
Public Library of Science (Plos) vol. 4 (1)
01-01-2008 2007
Evolution of genes and genomes on the Drosophila phylogenyClark AG Eisen MB Smith DR Bergman CM Oliver B Markow TA Kaufman TC Kellis M et al.
Nature,
Springer Nature vol. 450 (7167), 203-218.
01-11-2007 Five Drosophila Genomes Reveal Nonneutral Evolution and the Signature of Host Specialization in the Chemoreceptor SuperfamilyMcBride CS Arguello JR
Genetics,
Oxford University Press (OUP) vol. 177 (3), 1395-1416.
01-11-2007 Origination of Chimeric Genes through DNA-Level RecombinationArguello JR Fan C Long M
In
Gene and Protein Evolution,
Karger Medical and Scientific Publishers 01-01-2007 2006
Origination of an X-Linked Testes Chimeric Gene by Illegitimate Recombination in DrosophilaArguello JR Chen Y Yang S
Plos Genetics,
Public Library of Science (Plos) vol. 2 (5)
01-05-2006 2005
Genetic structure in the coral‐reef‐associated Banggai cardinalfish, Pterapogon kauderniHOFFMAN EA KOLM N ARGUELLO JR
Molecular Ecology,
Wiley vol. 14 (5), 1367-1375.
29-03-2005
Grants
Grants of specific relevance to the Centre for Evolutionary and Functional Genomics
Molecular and Cellular Evolution of Sensory Organs - GRANT TRANSFERRoman Arguello£59,906
Swiss National Science Foundation01-07-2024 - 30-06-2025
Research Group
PhD Students
- Tom Frankish
The Evolution and Molecular Control of Trunk Heterochronies in Annelid Larvae - Sarah Hume
Evolution of Olfactory Perception
