Publications
![Relevant Publication](/common/publications/images/fav.png)
Publications of specific relevance to the Centre for Bioengineering
2023
Verbruggen SW, Nolan J, Duffy MP, Pearce OMT, Jacobs CR and
Knight MM (2023).
A Novel Primary Cilium‐Mediated Mechanism Through which Osteocytes Regulate Metastatic Behavior of Both Breast and Prostate Cancer Cells. Advanced Science,
Wiley vol. 11 (2)
15-11-2023![Relevant Publication](/common/publications/images/fav.png)
Thompson CL, Hopkins T, Bevan C,
Screen HRC, Wright KT and
Knight MM (2023).
Human vascularised synovium-on-a-chip: a mechanically stimulated, microfluidic model to investigate synovial inflammation and monocyte recruitment. Biomedical Materials,
IOP Publishing vol. 18 (6)
10-10-2023![Relevant Publication](/common/publications/images/fav.png)
Nolan J, Pearce OMT,
Screen HRC,
Knight MM and
Verbruggen SW (2023).
Organ-on-a-Chip and Microfluidic Platforms for Oncology in the UK. Cancers,
MDPI vol. 15 (3)
19-01-20232022
![Relevant Publication](/common/publications/images/fav.png)
Meng H, Thompson CL, Coveney CR, Wann AK and
Knight MM (2022).
Techniques for Visualization and Quantification of Primary Cilia in Chondrocytes. Cartilage Tissue Engineering 157-176.
11-11-2022![Relevant Publication](/common/publications/images/fav.png)
Meng H, Fu S, Ferreira MB, Hou Y, Pearce OM, Gavara N and
Knight MM (2022).
YAP activation inhibits inflammatory signalling and cartilage breakdown associated with reduced primary cilia expression. Osteoarthritis and Cartilage,
Elsevier vol. 31 (5), 600-612.
08-11-2022![Relevant Publication](/common/publications/images/fav.png)
Hayward M-K, Allen MD, Gomm JJ, Goulding I, Thompson CL,
Knight MM, Marshall JF and Jones JL (2022).
Mechanostimulation of breast myoepithelial cells induces functional changes associated with DCIS progression to invasion. npj Breast Cancer,
Springer Nature vol. 8 (1)
20-09-2022![Relevant Publication](/common/publications/images/fav.png)
Badar W, Ali H, Brooker ON, Newham E, Snow T, Terrill NJ, Tozzi G, Fratzl P,
Knight MM and
Gupta HS (2022).
Collagen pre-strain discontinuity at the bone—Cartilage interface. PLOS ONE,
Public Library of Science (PLoS) vol. 17 (9)
15-09-2022![Relevant Publication](/common/publications/images/fav.png)
Heywood HK, Gardner L,
Knight MM and
Lee DA (2022).
Oscillations of the circadian clock protein, BMAL-1, align to daily cycles of mechanical stimuli: a novel means to integrate biological time within predictive in vitro model systems. In vitro models,
Springer Nature, 1-8.
31-08-20222021
![Relevant Publication](/common/publications/images/fav.png)
Inamdar SR, Prévost S, Terrill NJ,
Knight MM and
Gupta HS (2021).
Reversible changes in the 3D collagen fibril architecture during cyclic loading of healthy and degraded cartilage. Acta Biomaterialia,
Elsevier vol. 136, 314-326.
24-11-2021![Relevant Publication](/common/publications/images/fav.png)
Malacrida B, Delaine-Smith R, Nichols S, Maniati E, Jones RL,
Knight MM, Pearce OM and Balkwill FR (2021).
Abstract 2642: Using 3-Dimensional in vitro models to unravel the complexity of the metastatic microenvironment in high-grade serous ovarian cancer. 01-07-2021
Verbruggen SW, Thompson CL, Duffy MP, Lunetto S, Nolan J, Pearce OMT, Jacobs CR and
Knight MM (2021).
Mechanical Stimulation Modulates Osteocyte Regulation of Cancer Cell Phenotype. Cancers,
MDPI vol. 13 (12)
10-06-2021![Relevant Publication](/common/publications/images/fav.png)
Malacrida B, Nichols S, Maniati E, Jones R, Delanie-Smith R, Roozitalab R, Tyler EJ, Thomas M, Boot G, Mackerodt J, Lockley M,
Knight MM, Balkwill FR and Pearce OMT (2021).
A human multi-cellular model shows how platelets drive production of diseased extracellular matrix and tissue invasion. iScience,
Elsevier vol. 24 (6)
29-05-2021![Relevant Publication](/common/publications/images/fav.png)
Delaine-Smith RM, Maniati E, Malacrida B, Nichols S, Roozitalab R, Jones RR, Lecker LSM, Pearce OMT,
Knight MM and Balkwill FR (2021).
Modelling TGFβR and Hh pathway regulation of prognostic matrisome molecules in ovarian cancer. iScience,
Elsevier vol. 24 (6)
29-05-2021![Relevant Publication](/common/publications/images/fav.png)
Thompson C, Mcfie M, Chapple J, BEALES P and
Knight M (2021).
Polycystin-2 is required for chondrocyte mechanotransduction and traffics to the primary cilium in response to mechanical stimulation. International Journal of Molecular Sciences,
MDPI AG 21-04-2021![Relevant Publication](/common/publications/images/fav.png)
Wu H, Wang Z, Liu S, Meng H,
Shelton JC, Thompson CL, Fu S and
Knight MM (2021).
Sub-toxic levels of cobalt ions impair mechanostranduction via HDAC6-depedent primary cilia shortening. Biochem Biophys Res Commun 15-04-2021![bullet icon](/common/publications/images/bullet24.png)
Thompson CL, Fu S, Heywood HK,
Knight MM and Thorpe SD (2021).
Corrigendum: Mechanical Stimulation: A Crucial Element of Organ-on-Chip Models. Frontiers in Bioengineering and Biotechnology,
Frontiers vol. 9
18-02-2021![Relevant Publication](/common/publications/images/fav.png)
Delaine-Smith R, Maniati E, Malacrida B, Nichols S, Roozitalab R, Jones R, Lecker L, Pearce O,
Knight M and Balkwill F (2021).
Modelling TGFβR and Hh pathway regulation of prognostic matrisome molecules in ovarian cancer., Editors: Balkwill F.
biorxiv.org 02-02-2021![Relevant Publication](/common/publications/images/fav.png)
Fu S, Meng H, Inamdar S, Das B,
Gupta H,
Wang W, Thompson C and
Knight M (2021).
Activation of TRPV4 by mechanical, osmotic or pharmaceutical stimulation is anti-inflammatory blocking IL-1β mediated articular cartilage matrix destruction., Editors: Block JA.
Osteoarthritis and Cartilage,
Elsevier 01-01-2021![Relevant Publication](/common/publications/images/fav.png)
Malacrida B, Delaine-Smith R, Nichols S, Maniati E, Jones RL,
Knight MM, Pearce OM and Balkwill FR (2021).
Using 3-Dimensional in vitro models to unravel the complexity of the metastatic microenvironment in high-grade serous ovarian cancer. 01-01-20212020
![Relevant Publication](/common/publications/images/fav.png)
Thompson CL, Fu S, Heywood HK,
Knight MM and Thorpe SD (2020).
Mechanical Stimulation: A Crucial Element of Organ-on-Chip Models. Frontiers in Bioengineering and Biotechnology,
Frontiers Media SA vol. 8
10-12-2020![Relevant Publication](/common/publications/images/fav.png)
Zhang J, Guo Q, Li X, Li C, Wu K,
Abrahams I,
Yan H,
Knight MM,
Humphreys CJ and
Su L (2020).
Solution-Processed Epitaxial Growth of Arbitrary Surface Nanopatterns on Hybrid Perovskite Monocrystalline Thin Films. ACS Nano,
American Chemical Society 27-08-2020![Relevant Publication](/common/publications/images/fav.png)
Torres-Pérez JV, Naeem H, Thompson CL,
Knight MM and Novak P (2020).
Nanoscale mapping reveals functional differences in ion channels populating the membrane of primary cilia. Cellular Physiology and Biochemistry vol. 54 (1), 15-26.
10-01-20202019
![Relevant Publication](/common/publications/images/fav.png)
Fu S, Meng H, Freer F, Kwon J,
Shelton JC and
Knight MM (2019).
Sub-toxic levels of Co2+ are anti-inflammatory and protect cartilage from degradation caused by IL-1β. Clinical Biomechanics,
Elsevier vol. 79
24-12-2019![Relevant Publication](/common/publications/images/fav.png)
Walker RV, Keynton JL, Grimes DT, Sreekumar V, Williams DJ, Esapa C, Wu D,
Knight MM and Norris DP (2019).
Ciliary exclusion of Polycystin-2 promotes kidney cystogenesis in an autosomal dominant polycystic kidney disease model. Nature Communications,
Springer Nature vol. 10 (1)
06-09-2019![Relevant Publication](/common/publications/images/fav.png)
Inamdar SR, Barbieri E, Terrill NJ,
Knight MM and
Gupta HS (2019).
Proteoglycan degradation mimics static compression by altering the natural gradients in fibrillar organisation in cartilage. Acta Biomaterialia,
Elsevier vol. 97, 437-450.
30-07-2019![Relevant Publication](/common/publications/images/fav.png)
Delaine-Smith R, Wright N, Hanley C, Hanwell R, Bhome R, Bullock M, Drifka C, Eliceiri K, Thomas G,
Knight M, Mirnezami A and Peake N (2019).
Transglutaminase-2 Mediates the Biomechanical Properties of the Colorectal Cancer Tissue Microenvironment that Contribute to Disease Progression. Cancers,
MDPI AG 21-05-2019![Relevant Publication](/common/publications/images/fav.png)
Fu S, Thompson CL, Ali A,
Wang W, Chapple JP, Mitchison HM, Beales PL, Wann AKT and
Knight MM (2019).
Mechanical loading inhibits cartilage inflammatory signalling via an HDAC6 and IFT-dependent mechanism regulating primary cilia elongation. Osteoarthritis and Cartilage,
Elsevier vol. 27 (7), 1064-1074.
25-03-2019![Relevant Publication](/common/publications/images/fav.png)
Harris C, THORPE SD, Rushwan S, Wang W, THOMPSON C, Peacock J,
KNIGHT M, Gooptu B and Greenough A (2019).
An in vitro investigation of the inflammatory response to the strain amplitudes which occur during high frequency oscillation ventilation and conventional mechanical ventilation. Journal of Biomechanics,
Elsevier 22-03-2019![Relevant Publication](/common/publications/images/fav.png)
Delaine-Smith R, Wright N, Hanley CJ, Hanwell R, Bhome R, Bullock M, Drifka CR, Eliceiri KW, Thomas G,
Knight MM, Mirnezami AH and Peake NJ (2019).
Transglutaminase-2 mediates stromal biomechanics in colorectal cancer. 01-01-20192018
![Relevant Publication](/common/publications/images/fav.png)
O’Toole SM, Watson DS, Novoselova TV, Romano LEL, King PJ, Bradshaw TY, Thompson CL,
Knight MM, Sharp TV, Barnes MR, Srirangalingam U, Drake WM and Chapple JP (2018).
Oncometabolite induced primary cilia loss in pheochromocytoma. Endocrine Related Cancer,
Bioscientifica vol. 26 (1), 165-180.
05-09-2018![Relevant Publication](/common/publications/images/fav.png)
Rowson DT,
Shelton JC,
Screen HRC and
Knight MM (2018).
Mechanical loading induces primary cilia disassembly in tendon cells via TGFβ and HDAC6. Scientific Reports,
Springer Nature vol. 8 (1)
23-07-2018![Relevant Publication](/common/publications/images/fav.png)
Xu J, Nyga A, Li W, Zhang X, Gavara N,
Knight MM and
Shelton JC (2018).
Cobalt ions stimulate a fibrotic response through matrix remodelling, fibroblast contraction and release of pro-fibrotic signals from macrophages. European Cells and Materials vol. 36, 142-155.
01-07-2018![Relevant Publication](/common/publications/images/fav.png)
Kenny FN, Drymoussi Z, Delaine-Smith R, Kao AP, Laly AC,
Knight MM, Philpott MP and Connelly JT (2018).
Tissue stiffening promotes keratinocyte proliferation through activation of epidermal growth factor signaling. Journal of Cell Science vol. 131 (10), 215780-215780.
15-05-2018![Relevant Publication](/common/publications/images/fav.png)
Xu J, Yang J, Nyga A, Ehteramyan M, Moraga A, Wu Y, Zeng L,
Knight MM and
Shelton JC (2018).
Cobalt (II) ions and nanoparticles induce macrophage retention by ROS-mediated down-regulation of RhoA expression. Acta Biomater vol. 72, 434-446.
09-04-2018![Relevant Publication](/common/publications/images/fav.png)
Pearce OMT, Nichols S, Delaine-Smith R, Jones RR, Maniati E, Rootizalab R, Mackerodt J,
Knight MM and Balkwill FR (2018).
Investigating drivers of the tumour matrisome, and their role in disease progression. 01-01-20182017
![Relevant Publication](/common/publications/images/fav.png)
Pearce OMT, Delaine-Smith R, Maniati E, Nichols S, Wang J, Böhm S, Rajeeve V, Ullah D, Chakravarty P, Jones RR, Montfort A, Dowe T, Gribben J, Jones JL, Kocher HM, Serody JS, Vincent BG, Connelly J, Brenton JD, Chelala C,
et al. (2017).
Deconstruction of a metastatic tumor microenvironment reveals a common matrix response in human cancers. Cancer Discov 01-12-2017![Relevant Publication](/common/publications/images/fav.png)
Thompson CL, Plant JC, Wann AK, Bishop CL, Novak P, Mitchison HM, Beales PL, Chapple JP and
Knight MM (2017).
Chondrocyte expansion is associated with loss of primary cilia and disrupted hedgehog signalling. Eur Cell Mater vol. 34, 128-141.
20-09-2017![Relevant Publication](/common/publications/images/fav.png)
Inamdar SR, Knight DP, Terrill NJ, Karunaratne A, Cacho-Nerin F,
Knight MM and
Gupta HS (2017).
The Secret Life of Collagen: Temporal Changes in Nanoscale Fibrillar Pre-Strain and Molecular Organization During Physiological Loading of Cartilage. ACS Nano 11-08-2017![Relevant Publication](/common/publications/images/fav.png)
Zhang J, Dalbay MT, Luo X, Vrij E, Barbieri D, Moroni L, de Bruijn JD, van Blitterswijk CA, Chapple JP,
Knight MM and Yuan H (2017).
Topography of calcium phosphate ceramics regulates primary cilia length and TGF receptor recruitment associated with osteogenesis. Acta Biomater vol. 57, 487-497.
15-07-2017![Relevant Publication](/common/publications/images/fav.png)
Balkwill FR, Pearce OM, Delaine-Smith R, Maniati E, Nichols S, Wang J,
Bessant C and
Knight M (2017).
Abstract 5558: Deconstruction of a human tumor microenvironment. 01-07-2017![Relevant Publication](/common/publications/images/fav.png)
Harris C, Rushwan S, Wang W, Thorpe S, Thompson C, Peacock J,
Knight M, Gooptu B and Greenough A (2017).
P07 Interleukin response to cyclical mechanical stretch with models of different neonatal ventilation modes. Plenary.
01-05-2017![Relevant Publication](/common/publications/images/fav.png)
Gambassi S, Geminiani M, Thorpe SD, Bernardini G, Millucci L, Braconi D, Orlandini M, Thompson CL, Petricci E, Manetti F, Taddei M,
Knight MM and Santucci A (2017).
Smoothened‐antagonists reverse homogentisic acid‐induced alterations of Hedgehog signaling and primary cilium length in alkaptonuria. Journal of Cellular Physiology,
Wiley vol. 232 (11), 3103-3111.
29-03-2017![Relevant Publication](/common/publications/images/fav.png)
THORPE SD, Gambassi S, Thompson CL, Chandrakumar C, Santucci A and
Knight MM (2017).
Reduced Primary Cilia Length and Altered Arl13b Expression Are Associated with Deregulated Chondrocyte Hedgehog Signalling in Alkaptonuria. Journal of Cellular Physiology,
John Wiley & Sons Inc. 03-02-2017
Knight MM (2017).
Primary cilia mechanobiology. 01-01-2017![Relevant Publication](/common/publications/images/fav.png)
Gooptu B, Rushwan S, Wang W, Harris C, Thorpe S,
Knight M and Sethi T (2017).
A Cd98hc-Dependent Mechanism Mediates Pro-Inflammatory Cytokine Release In Cell And Animal Models Of Lung Injury. 01-01-2017![Relevant Publication](/common/publications/images/fav.png)
Thompson CL, Chapple JP, Beales PL, Mitchison HM, Ramachandran M and
Knight MM (2017).
Polycystins are required for primary cilia-mediated mechanotransduction in chondrocytes. 01-01-2017![Relevant Publication](/common/publications/images/fav.png)
Rowson DT,
Knight MM and
Screen HRC (2017).
Cyclic loading leads to primary cilia disassembly in human tenocytes. 01-01-20172016
![Relevant Publication](/common/publications/images/fav.png)
Delaine-Smith RM, Burney S, Balkwill FR and
Knight MM (2016).
Experimental validation of a flat punch indentation methodology calibrated against unconfined compression tests for determination of soft tissue biomechanics. Journal of the Mechanical Behavior of Biomedical Materials,
Elsevier vol. 60, 401-415.
01-07-2016![Relevant Publication](/common/publications/images/fav.png)
Sliogeryte K, Botto L,
Lee DA and
Knight MM (2016).
Chondrocyte dedifferentiation increases cell stiffness by strengthening membrane-actin adhesion. Osteoarthritis and Cartilage,
Elsevier vol. 24 (5), 912-920.
01-05-2016![Relevant Publication](/common/publications/images/fav.png)
Kelly T-AN, Thompson CL, Tan E, Wann AK, Thorpe SD, Chapple JP, Hung CT and
Knight MM (2016).
Chondrocyte dedifferentiation down regulates mechano-responsiveness and hedgehog signalling associated with changes in primary cilia structure. World Congress of the Osteoarthritis-Research-Society-International (OARSI) on Osteoarthritis 31 Mar 2016 - 3 Apr 2016.
01-04-2016![Relevant Publication](/common/publications/images/fav.png)
Thorpe SD, Gambassi S, Patel R, Santucci A and
Knight MM (2016).
Changes in chondrocyte primary cilia structure and function are associated with altered mechanoregulation in Alkaptonuria. 01-04-2016![Relevant Publication](/common/publications/images/fav.png)
Rowson D,
Knight MM and
Screen HRC (2016).
Zonal variation in primary cilia elongation correlates with localized biomechanical degradation in stress deprived tendon. J Orthop Res vol. 34 (12), 2146-2153.
23-03-2016
KNIGHT MM,
wang W, wang Z, wann A, thompson C and hassen A (2016).
IFT88 influences chondrocyte actin organization and biomechanics. Osteoarthritis and Cartilage 01-03-2016![Relevant Publication](/common/publications/images/fav.png)
Thompson CL, Wiles A, Poole CA and
Knight MM (2016).
Lithium chloride modulates chondrocyte primary cilia and inhibits Hedgehog signaling. FASEB Journal vol. 30 (2), 716-726.
01-02-2016![Relevant Publication](/common/publications/images/fav.png)
Sliogeryte K, Thorpe SD, Wang Z, Thompson CL, Gavara N and
Knight MM (2016).
Differential effects of LifeAct-GFP and actin-GFP on cell mechanics assessed using micropipette aspiration. Journal of Biomechanics,
Elsevier vol. 49 (2), 310-317.
25-01-2016
Knight M, Buchholz N and Bourdoumis A (2016).
Physiology of urethral flow. Handbook of Urinary Stents: Basic Science and Clinical Applications 219-219.
01-01-20162015
![Relevant Publication](/common/publications/images/fav.png)
Thompson CL, Patel R, Kelly T-AN, Wann AKT, Hung CT, Chapple JP and
Knight MM (2015).
Hedgehog signalling does not stimulate cartilage catabolism and is inhibited by Interleukin-1β. Arthritis Research & Therapy vol. 17 (1)
24-12-2015![Relevant Publication](/common/publications/images/fav.png)
Tan AR, VandenBerg CD, Attur M, Abramson SB,
Knight MM, Bulinski JC, Ateshian GA, Cook JL and Hung CT (2015).
Cytokine preconditioning of engineered cartilage provides protection against interleukin-1 insult. Arthritis Res Ther vol. 17, 361-361.
14-12-2015![Relevant Publication](/common/publications/images/fav.png)
Thompson CL, Poole CA and
Knight MM (2015).
Lithium chloride modulates chondrocyte primary cilia and inhibits Hedgehog signaling. The FASEB Journal,
Federation of American Society of Experimental Biology vol. 100 (4), A39-A40.
23-10-2015
KNIGHT MM, Thompson CL, Yasmin H, Varone A, Wiles A and Poole CA (2015).
Lithium chloride prevents interleukin- 1β induced cartilage degradation and loss of mechanical properties. Journal of Orthopaedic Research,
Wiley: 12 months 01-10-2015![Relevant Publication](/common/publications/images/fav.png)
CHEN J, BADER DL,
LEE DA and
KNIGHT MM (2015).
FINITE ELEMENT ANALYSIS OF MECHANICAL DEFORMATION OF CHONDROCYTE TO 2D SUBSTRATE AND 3D SCAFFOLD. Journal of Mechanics in Medicine and Biology,
World Scientific Publishing vol. 15 (05)
01-10-2015![Relevant Publication](/common/publications/images/fav.png)
Dalbay MT, Thorpe SD, Connelly JT, Chapple JP and
Knight MM (2015).
Adipogenic Differentiation of hMSCs is Mediated by Recruitment of IGF‐1r Onto the Primary Cilium Associated With Cilia Elongation. Stem Cells,
Oxford University Press (OUP) vol. 33 (6), 1952-1961.
21-05-20152014
![Relevant Publication](/common/publications/images/fav.png)
Sliogeryte K, Thorpe SD,
Lee DA, Botto L and
Knight MM (2014).
Stem cell differentiation increases membrane-actin adhesion regulating cell blebability, migration and mechanics. Scientific Reports,
Springer Nature vol. 4 (1)
04-12-2014![Relevant Publication](/common/publications/images/fav.png)
Wang Z, Irianto J, Kazun S,
Wang W and
Knight MM (2014).
The rate of hypo-osmotic challenge influences regulatory volume decrease (RVD) and mechanical properties of articular chondrocytes. Osteoarthritis and Cartilage,
Elsevier vol. 23 (2), 289-299.
11-11-2014![Relevant Publication](/common/publications/images/fav.png)
Rowson D,
Knight M and
Screen H (2014).
89 Primary Cilia In Tenocytes From The Inter-fascicular Matrix And The Fascicular Matrix. British Journal of Sports Medicine,
BMJ vol. 48 (Suppl 2), a58-a59.
01-09-2014![Relevant Publication](/common/publications/images/fav.png)
Wann AKT, Chapple JP and
Knight MM (2014).
The primary cilium influences interleukin-1β-induced NFκB signalling by regulating IKK activity. Cell Signal vol. 26 (8), 1735-1742.
01-08-2014![Relevant Publication](/common/publications/images/fav.png)
Irianto J,
Lee DA and
Knight MM (2014).
Quantification of chromatin condensation level by image processing. Med Eng Phys vol. 36 (3), 412-417.
01-03-2014![Relevant Publication](/common/publications/images/fav.png)
Thompson CL, Chapple JP and
Knight MM (2014).
Primary cilia disassembly down-regulates mechanosensitive hedgehog signalling: a feedback mechanism controlling ADAMTS-5 expression in chondrocytes. Osteoarthritis Cartilage vol. 22 (3), 490-498.
01-03-2014![Relevant Publication](/common/publications/images/fav.png)
Irianto J, Ramaswamy G, Serra R and
Knight MM (2014).
Depletion of chondrocyte primary cilia reduces the compressive modulus of articular cartilage. J Biomech vol. 47 (2), 579-582.
22-01-2014![Relevant Publication](/common/publications/images/fav.png)
Shaheen T, Edirisinghe T, Gabriel M, Bourdoumis A, Buchholz N and
Knight M (2014).
In vitro encrustation of a semi-permanent polymer-covered nitinol ureter stent: an artificial urine model. UROLITHIASIS vol. 42 (3), 203-207.
01-01-20142013
![Relevant Publication](/common/publications/images/fav.png)
Hosny NA, Song M, Connelly JT, Ameer-Beg S,
Knight MM and Wheeler AP (2013).
Correction: Super-Resolution Imaging Strategies for Cell Biologists Using a Spinning Disk Microscope. PLOS ONE,
Public Library of Science (PLoS) vol. 8 (12)
30-12-2013![Relevant Publication](/common/publications/images/fav.png)
McMurray RJ, Wann AKT, Thompson CL, Connelly JT and
Knight MM (2013).
Surface topography regulates wnt signaling through control of primary cilia structure in mesenchymal stem cells. Sci Rep vol. 3
18-12-2013![Relevant Publication](/common/publications/images/fav.png)
Wann AK, Thompson CL, Chapple JP and
Knight MM (2013).
Interleukin-1β sequesters hypoxia inducible factor 2α to the primary cilium. Cilia vol. 2 (1)
13-12-2013![Relevant Publication](/common/publications/images/fav.png)
Shafat M, Rajakumar K, Syme H, Buchholz N and
Knight MM (2013).
Stent encrustation in feline and human artificial urine: does the low molecular weight composition account for the difference? Urolithiasis vol. 41 (6), 481-486.
01-11-2013![Relevant Publication](/common/publications/images/fav.png)
Irianto J, Swift J, Martins RP, McPhail GD,
Knight MM, Discher DE and
Lee DA (2013).
Osmotic challenge drives rapid and reversible chromatin condensation in chondrocytes. Biophys J vol. 104 (4), 759-769.
19-02-2013
Knight MM (2013).
THE ROLE OF PRIMARY CILIA IN CARTILAGE HEALTH AND DISEASE. 01-01-2013![Relevant Publication](/common/publications/images/fav.png)
Hosny NA, Song M, Connelly JT, Ameer-Beg S,
Knight MM and Wheeler AP (2013).
Super-resolution imaging strategies for cell biologists using a spinning disk microscope. PLoS One vol. 8 (10)
01-01-2013![Relevant Publication](/common/publications/images/fav.png)
Hernandez-Hernandez V, Pravincumar P, Diaz-Font A, May-Simera H, Jenkins D,
Knight M and Beales PL (2013).
Bardet-Biedl syndrome proteins control the cilia length through regulation of actin polymerization. HUMAN MOLECULAR GENETICS vol. 22 (19), 3858-3868.
01-01-2013![Relevant Publication](/common/publications/images/fav.png)
Hosny NA, Song M,
Knight MM and Wheeler AP (2013).
Super-resolution imaging strategies for Cell Biologists using a spinning disk microscope. MOLECULAR BIOLOGY OF THE CELL vol. 24
01-01-20132012
![Relevant Publication](/common/publications/images/fav.png)
Prodromou NV, Thompson CL, Osborn DPS, Cogger KF, Ashworth R,
Knight MM, Beales PL and Chapple JP (2012).
Heat shock induces rapid resorption of primary cilia. Development,
The Company of Biologists vol. 139 (24), e2408-e2408.
15-12-2012![Relevant Publication](/common/publications/images/fav.png)
Prodromou NV, Thompson CL, Osborn DPS, Cogger KF, Ashworth R,
Knight MM, Beales PL and Chapple JP (2012).
Heat shock induces rapid resorption of primary cilia. Journal of Cell Science vol. 125 (18), 4297-4305.
01-12-2012![Relevant Publication](/common/publications/images/fav.png)
Thompson C, Prodromou N, Osborn D, Ashworth R,
Knight M, Beales P and Chapple J (2012).
Heat-shock induces rapid resorption of primary cilia. Cilia,
Springer Nature vol. 1 (Suppl 1)
01-11-2012![Relevant Publication](/common/publications/images/fav.png)
Thompson C, Chapple J and
Knight M (2012).
Mechanical strain disrupts primary cilia structure and modulates hedgehog signalling in adult chondrocytes. Cilia,
Springer Nature vol. 1 (Suppl 1)
01-11-2012![Relevant Publication](/common/publications/images/fav.png)
McMurray R and
Knight M (2012).
Topographical regulation of primary cilia orientation and length in mesenchymal stem cells. Cilia,
Springer Nature vol. 1 (Suppl 1)
01-11-2012![Relevant Publication](/common/publications/images/fav.png)
Wann A and
Knight M (2012).
A role for IFT88/the primary cilium in the inflammatory response to interleukin-1. Cilia,
Springer Nature vol. 1 (Suppl 1)
01-11-2012![Relevant Publication](/common/publications/images/fav.png)
Wann A, Zuo N, Haycraft C, Jensen C, Poole C, McGlashan S and
Knight M (2012).
The primary cilium conducts chondrocyte mechanotransduction. Cilia,
Springer Nature vol. 1 (Suppl 1)
01-11-2012![Relevant Publication](/common/publications/images/fav.png)
Hernandez V, Pravincumar P, Diaz-Font A, May-Simera H, Jenkins D,
Knight M and Beales P (2012).
Bardet-Biedl syndrome proteins control cilia length through regulation of actin polymerisation. Cilia,
Springer Nature vol. 1 (Suppl 1)
01-11-2012![Relevant Publication](/common/publications/images/fav.png)
Wheeler APS, Morad S, Buchholz N and
Knight MM (2012).
The Shape of the Urine Stream - From Biophysics to Diagnostics. PLoS ONE vol. 7 (10)
16-10-2012![Relevant Publication](/common/publications/images/fav.png)
Chen J, Irianto J, Inamdar S, Pravincumar P,
Lee DA, Bader DL and
Knight MM (2012).
Cell mechanics, structure, and function are regulated by the stiffness of the three-dimensional microenvironment. Biophys J vol. 103 (6), 1188-1197.
19-09-2012![Relevant Publication](/common/publications/images/fav.png)
Pravincumar P, Bader DL and
Knight MM (2012).
Viscoelastic Cell Mechanics and Actin Remodelling Are Dependent on the Rate of Applied Pressure. PLoS ONE vol. 7 (9)
11-09-2012![Relevant Publication](/common/publications/images/fav.png)
Wann AKT and
Knight MM (2012).
Primary cilia elongation in response to interleukin-1 mediates the inflammatory response. Cellular and Molecular Life Sciences vol. 69 (17), 2967-2977.
01-09-2012![Relevant Publication](/common/publications/images/fav.png)
Bonzani IC, Campbell JJ,
Knight MM, Williams A,
Lee DA, Bader DL and Stevens MM (2012).
Dynamic compressive strain influences chondrogenic gene expression in human periosteal cells: a case study. J Mech Behav Biomed Mater vol. 11, 72-81.
01-07-2012![Relevant Publication](/common/publications/images/fav.png)
Pravincumar P, Bader D and
Knight M (2012).
PRESSURE RATE SENSITIVE VISCOELASTIC CELL DEFORMATION INVOLVES ACTIN REMODELLING. Journal of Biomechanics,
Elsevier vol. 45
01-07-2012![Relevant Publication](/common/publications/images/fav.png)
Wann AKT, Zuo N, Haycraft CJ, Jensen CG, Poole CA, McGlashan SR and
Knight MM (2012).
Primary cilia mediate mechanotransduction through control of ATP-induced Ca2+ signaling in compressed chondrocytes. FASEB Journal vol. 26 (4), 1663-1671.
01-04-2012![Relevant Publication](/common/publications/images/fav.png)
Maeda E, Ye S, Wang W, Bader DL,
Knight MM and
Lee DA (2012).
Gap junction permeability between tenocytes within tendon fascicles is suppressed by tensile loading. Biomechanics and Modeling in Mechanobiology vol. 11 (3-4), 439-447.
01-03-2012![Relevant Publication](/common/publications/images/fav.png)
Gladman SJ, Huang W, Lim SN, Dyall SC, Boddy S, Kang JX,
Knight MM, Priestley JV and Michael-Titus AT (2012).
Improved outcome after peripheral nerve injury in mice with increased levels of endogenous Omega-3 polyunsaturated fatty acids. Journal of Neuroscience vol. 32 (2), 563-571.
11-01-2012![Relevant Publication](/common/publications/images/fav.png)
Hosny NA,
Lee DA and
Knight MM (2012).
Single photon counting fluorescence lifetime detection of pericellular oxygen concentrations. J Biomed Opt vol. 17 (1)
01-01-2012![Relevant Publication](/common/publications/images/fav.png)
Wann AKT, Thompson C and
Knight MM (2012).
The Role of the Primary Cilium in Chondrocyte Response to Mechanical Loading. Mechanically Gated Channels and their Regulation 405-426.
01-01-2012![Relevant Publication](/common/publications/images/fav.png)
McMurray R and
Knight MM (2012).
Topographical regulation of primary cilia orientation and length in mesenchymal stem cells. Cilia vol. 1 (Suppl 1), P34-P34.
01-01-2012![Relevant Publication](/common/publications/images/fav.png)
Thompson CL, Prodromou NV, Osborn DP, Ashworth R,
Knight MM, Beales PL and Chapple JP (2012).
Heat-shock induces rapid resorption of primary cilia. Cilia vol. 1 (Suppl 1), P52-P52.
01-01-20122011
![Relevant Publication](/common/publications/images/fav.png)
Gladman S, Lim SN, Dyall S,
Knight MM, Priestley JV and Michael-Titus AT (2011).
Omega-3 fatty acids and acute neurological trauma: A perspective on clinical translation. OCL - Oleagineux Corps Gras Lipides vol. 18 (6), 317-323.
01-11-2011![Relevant Publication](/common/publications/images/fav.png)
Gabriel CEL, Nedilko T, Paulose PA, Bach C, Buchholz N and
Knight MM (2011).
E84 Can Shockwave lithotripsy remove encrustation from ureteric nitinol stents? European Urology Open Science,
Elsevier vol. 10 (7)
01-10-2011![Relevant Publication](/common/publications/images/fav.png)
Edirisinghe TY,
Knight MM, Buchholz N and Bach C (2011).
E70 The influence of extracorporeal shock wave lithotripsy on tissue viability around metallic ureteral stents. European Urology Open Science,
Elsevier vol. 10 (7)
01-10-2011![Relevant Publication](/common/publications/images/fav.png)
Shafat M, Nedilko T, Syme H, Buchholz N and
Knight MM (2011).
E189 Does the composition of feline urine prevent calcium oxalate encrustation of urethral stents? European Urology Open Science,
Elsevier vol. 10 (7), 517-518.
01-10-2011![Relevant Publication](/common/publications/images/fav.png)
Nedilko T, Paulose PA, Buchholz N and
Knight MM (2011).
E75 Comparison of encrustation rates between ureteric metal stents and Double J stents. European Urology Open Science,
Elsevier vol. 10 (7)
01-10-2011![Relevant Publication](/common/publications/images/fav.png)
Maeda E, Ye S,
Wang W, Bader DL,
Knight MM and
Lee DA (2011).
Gap junction permeability between tenocytes within tendon fascicles is suppressed by tensile loading. Biomechanics and Modeling in Mechanobiology, 1-9.
01-01-2011
Lee DA,
Knight MM, Campbell JJ and Bader DL (2011).
Stem cell mechanobiology. J Cell Biochem vol. 112 (1), 1-9.
01-01-20112010
![Relevant Publication](/common/publications/images/fav.png)
Gladman SJ, Ward RE, Michael-Titus AT,
Knight MM and Priestley JV (2010).
The effect of mechanical strain or hypoxia on cell death in subpopulations of rat dorsal root ganglion neurons in vitro. Neuroscience vol. 171 (2), 577-587.
01-12-2010![Relevant Publication](/common/publications/images/fav.png)
Vaughan NM, Grainger J, Bader DL and
Knight MM (2010).
The potential of pulsed low intensity ultrasound to stimulate chondrocytes matrix synthesis in agarose and monolayer cultures. Medical and Biological Engineering and Computing vol. 48 (12), 1215-1222.
01-12-2010![Relevant Publication](/common/publications/images/fav.png)
Wann AKT, Mistry J, Blain EJ, Michael-Titus AT and
Knight MM (2010).
Eicosapentaenoic acid and docosahexaenoic acid reduce interleukin-1β-mediated cartilage degradation. Arthritis Research and Therapy vol. 12 (6)
08-11-2010![Relevant Publication](/common/publications/images/fav.png)
Heywood HK,
Knight MM and
Lee DA (2010).
Both superficial and deep zone articular chondrocyte subpopulations exhibit the crabtree effect but have different basal oxygen consumption rates. Journal of Cellular Physiology vol. 223 (3), 630-639.
01-06-2010![Relevant Publication](/common/publications/images/fav.png)
Garcia M and
Knight MM (2010).
Cyclic loading opens hemichannels to release ATP as part of a chondrocyte mechanotransduction pathway. Journal of Orthopaedic Research vol. 28 (4), 510-515.
01-04-2010![Relevant Publication](/common/publications/images/fav.png)
Ye S, Maeda E,
Knight M,
Lee D, Bader D and
Wang W (2010).
A compartment model to evaluate the permeability of gap junctions between tenocytes in tendon fascicles. FASEB JOURNAL vol. 24
01-01-2010![Relevant Publication](/common/publications/images/fav.png)
Bader DL and
Knight MM (2010).
Measuring the biomechanical properties of cartilage cells. 01-01-2010![Relevant Publication](/common/publications/images/fav.png)
McGlashan SR,
Knight MM,
Chowdhury TT, Joshi P, Jensen CG, Kennedy S and Poole CA (2010).
Mechanical loading modulates chondrocyte primary cilia incidence and length. Cell Biology International vol. 34 (5), 441-446.
01-01-2010![Relevant Publication](/common/publications/images/fav.png)
Archer C, Ralphs J, Säämänen A-M, Arokoski JPA, Jurvelin JS, Kiviranta I, Hinz B, Hunziker EB, Bader DL,
Knight MM, Dell’accio F, Vincent TL, Aigner T, Schmitz N, Söder S, McIlwraith CW, Hangody L, Kish G, Koreny T, Hangody LR,
et al. (2010).
Contributor contact details. Regenerative Medicine and Biomaterials for the Repair of Connective Tissues xiii-xvii.
01-01-2010![Relevant Publication](/common/publications/images/fav.png)
Bader DL and
Knight MM (2010).
4 Measuring the biomechanical properties of cartilage cells. Regenerative Medicine and Biomaterials for the Repair of Connective Tissues 106-136.
01-01-2010![Relevant Publication](/common/publications/images/fav.png)
Maeda E, Ye S,
Knight M,
Wang W, Bader D and Lee D (2010).
1P338 1J1450 Mechano-regulation of gap junction communications between tenocytes within isolated fascicles(Bioengineering,Oral Presentations,The 48th Annual Meeting of the Biophysical Society of Japan). Seibutsu Butsuri,
Biophysical Society of Japan vol. 50 (supplement2)
01-01-20102009
Knight MM, Mcglashan SR, Garcia M, Jensen CG and Poole CA (2009).
Articular chondrocytes express connexin 43 hemichannels and P2 receptors - A putative mechanoreceptor complex involving the primary cilium? Journal of Anatomy vol. 214 (2), 275-283.
05-02-20092008
![Relevant Publication](/common/publications/images/fav.png)
Bader DL and
Knight MM (2008).
Biomechanical analysis of structural deformation in living cells. Medical and Biological Engineering and Computing vol. 46 (10), 951-963.
27-08-2008![Relevant Publication](/common/publications/images/fav.png)
Pingguan-Murphy B and
Knight MM (2008).
Mechanosensitive Purinergic Calcium Signalling in Articular Chondrocytes. Mechanosensitive Ion Channels 235-251.
01-01-20082007
![Relevant Publication](/common/publications/images/fav.png)
Campbell JJ, Blain EJ,
Chowdhury TT and
Knight MM (2007).
Loading alters actin dynamics and up-regulates cofilin gene expression in chondrocytes. Biochemical and Biophysical Research Communications vol. 361 (2), 329-334.
21-09-2007
KNIGHT MM, Chowdhury TT, Campbell JJ and Blain EJ (2007).
Loading alters actin dynamics and up-regulates cofilin gene expression in chondrocytes. Biochemical and Biophysical Research Communications vol. 361 (21), 329-334.
01-09-2007![Relevant Publication](/common/publications/images/fav.png)
Campbell JJ and
Knight MM (2007).
An improved confocal FRAP technique for the measurement of long-term actin dynamics in individual stress fibers. Microscopy Research and Technique vol. 70 (12), 1034-1040.
01-01-20072006
Chowdhury TT and
Knight MM (2006).
Purinergic pathway suppresses the release of NO and stimulates proteoglycan synthesis in chondrocyte/agarose constructs subjected to dynamic compression. Journal of Cellular Physiology vol. 209 (3), 845-853.
01-12-2006![Relevant Publication](/common/publications/images/fav.png)
Pingguan-Murphy B, El-Azzeh M, Bader DL and
Knight MM (2006).
Cyclic compression of chondrocytes modulates a purinergic calcium signalling pathway in a strain rate- and frequency-dependent manner. Journal of Cellular Physiology vol. 209 (2), 389-397.
01-11-2006![Relevant Publication](/common/publications/images/fav.png)
Hakimi O, Knight DP,
Knight MM, Grahn MF and Vadgama P (2006).
Ultrastructure of insect and spider cocoon silks. Biomacromolecules vol. 7 (10), 2901-2908.
01-10-2006![Relevant Publication](/common/publications/images/fav.png)
Bomzon Z,
Knight MM, Bader DL and Kimmel E (2006).
Mitochondrial dynamics in chondrocytes and their connection to the mechanical properties of the cytoplasm. Journal of Biomechanical Engineering vol. 128 (5), 674-679.
01-10-2006![Relevant Publication](/common/publications/images/fav.png)
Ohashi T, Hagiwara M, Bader DL and
Knight MM (2006).
Intracellular mechanics and mechanotransduction associated with chondrocyte deformation during pipette aspiration. Biorheology vol. 43 (3-4), 201-214.
18-08-2006
Knight MM, Bomzon Z, Kimmel E, Sharma AM,
Lee DA and Bader DL (2006).
Chondrocyte deformation induces mitochondrial distortion and heterogeneous intracellular strain fields. BIOMECH MODEL MECHAN vol. 5 (2-3), 180-191.
01-06-2006
Knight MM, Toyoda T,
Lee DA and Bader DL (2006).
Mechanical compression and hydrostatic pressure induce reversible changes in actin cytoskeletal organisation in chondrocytes in agarose. J Biomech vol. 39 (8), 1547-1551.
01-01-2006![Relevant Publication](/common/publications/images/fav.png)
Bader DL,
Lee DA and
Knight MM (2006).
Chondrocyte Deformation and Mechanotransduction in Cartilage Model Systems(International Workshop 2). The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME,
Japan Society of Mechanical Engineers vol. 2005.18, 2-3.
01-01-2006![Relevant Publication](/common/publications/images/fav.png)
Bomzon Z,
Knight MM, Bader DL and Kimmel E (2006).
Probing mechanical heterogeneity in chondrocytes using passive microtheology. Journal of Biomechanics,
Elsevier vol. 39
01-01-20062005
![Relevant Publication](/common/publications/images/fav.png)
Pingguan-Murphy B,
Lee DA, Bader DL and
Knight MM (2005).
Activation of chondrocytes calcium signalling by dynamic compression is independent of number of cycles. Arch Biochem Biophys vol. 444 (1), 45-51.
01-12-20052004
![Relevant Publication](/common/publications/images/fav.png)
Sawae Y,
Shelton JC, Bader DL and
Knight MM (2004).
Confocal analysis of local and cellular strains in chondrocyte-agarose constructs subjected to mechanical shear. Ann Biomed Eng vol. 32 (6), 860-870.
01-06-2004
Lee DA and
Knight MM (2004).
Mechanical loading of chondrocytes embedded in 3D constructs: in vitro methods for assessment of morphological and metabolic response to compressive strain. Methods Mol Med vol. 100, 307-324.
01-01-2004![Relevant Publication](/common/publications/images/fav.png)
Holloway I, Kayser M,
Lee DA, Bader DL, Bentley G and
Knight MM (2004).
Increased presence of cells with multiple elongated processes in osteoarthritic femoral head cartilage. Osteoarthritis Cartilage vol. 12 (1), 17-24.
01-01-2004
Lee DA and
Knight MM (2004).
Mechanical Loading of Chondrocytes Embedded in 3D Constructs. Cartilage and Osteoarthritis 307-324.
01-01-20042003
Knight MM, Roberts SR,
Lee DA and Bader DL (2003).
Live cell imaging using confocal microscopy induces intracellular calcium transients and cell death. Am J Physiol Cell Physiol vol. 284 (4), C1083-C1089.
01-04-2003![Relevant Publication](/common/publications/images/fav.png)
Bader DL,
SHELTON JC,
Knight MM and Sawae Y (2003).
Confocal Analysis of Local and Cellular Strains in Chondrocyte - Agarose Constructs Subjected to Shear. J Biochemical Engineering ASME 01-01-20032002
Knight MM, Toyoda T, Bader DL and
Lee DA (2002).
Mechanical strain and hydrostatic pressure induce reversible changes in actin cytoskeletal organisation in chondrocytes in agarose. 01-12-2002
Knight MM, Roberts SR,
Lee DA and Bader DL (2002).
Light-induced calcium signalling in chondrocytes. 01-12-2002
Knight MM, van de Breevaart Bravenboer J,
Lee DA, van Osch GJVM, Weinans H and Bader DL (2002).
Cell and nucleus deformation in compressed chondrocyte-alginate constructs: temporal changes and calculation of cell modulus. Biochim Biophys Acta vol. 1570 (1), 1-8.
15-02-2002
Knight MM, Roberts SR,
LEE DA and Bader DL (2002).
Light-induced calcium signalling in chondrocytes. TCES 2002 Annual meeting of the UK Tissue and Cell Engineering Society University of Glasgow, Scotland 19 Sep 2002 - 20 Sep 2002.
01-01-2002![Relevant Publication](/common/publications/images/fav.png)
Holloway I,
Knight MM,
LEE DA, Bader DL and Bentley G (2002).
Changes in cell morphology and cytoskeletal organisation in osteoarthritic cartilage. ECM III Cartilage & Joint repair Tutorials, Basic Research & Clinical Methods Davos, Switzerland 1 Jul 2002 - 3 Jul 2002.
01-01-2002
Knight MM, Toyoda T,
LEE DA and Bader DL (2002).
Mechanical strain and hydrostatic pressure induce reversible changes in actin cytoskeletal organisation in chondrocytes in agarose. 48th Annual Meeting of the Orthopaedic Research Society.
01-01-2002![Relevant Publication](/common/publications/images/fav.png)
Holloway I,
Knight MM,
LEE DA, Bader DL and Bentley G (2002).
Characterisation of cell morphology, cytoskeletal organization and apoptosis in human osteoarthritic cartilage. 48th Annual Meeting of the Orthopaedic Research Society.
01-01-2002![Relevant Publication](/common/publications/images/fav.png)
Bader DL, Ohashi T,
Knight MM,
Lee DA and Sato M (2002).
Deformation properties of articular chondrocytes: a critique of three separate techniques. 01-01-20022001
Knight MM, Ross JM, Sherwin AF,
Lee DA, Bader DL and Poole CA (2001).
Chondrocyte deformation within mechanically and enzymatically extracted chondrons compressed in agarose. Biochim Biophys Acta vol. 1526 (2), 141-146.
03-05-2001
Knight MM, Idowu BD,
Lee DA and Bader DL (2001).
Temporal changes in cytoskeletal organisation within isolated chondrocytes quantified using a novel image analysis technique. Med Biol Eng Comput vol. 39 (3), 397-404.
01-05-2001![Relevant Publication](/common/publications/images/fav.png)
Roberts SR,
Knight MM,
Lee DA and Bader DL (2001).
Mechanical compression influences intracellular Ca2+ signaling in chondrocytes seeded in agarose constructs. J Appl Physiol (1985) vol. 90 (4), 1385-1391.
01-04-2001![Relevant Publication](/common/publications/images/fav.png)
Bouten CV,
Knight MM,
Lee DA and Bade DL (2001).
Compressive deformation and damage of muscle cell subpopulations in a model system. Ann Biomed Eng vol. 29 (2), 153-163.
01-02-2001
Knight MM, van de Breevaart Brevenboer J, van Osch G, Weinans H,
LEE DA and Bader DL (2001).
Temporal changes in cell and nucleus deformation in isolated chondrocytes compressed in alginate scaffolds. 47th Annual Meeting, Orthopaedic Research Society San Francisco, California 25 Feb 2001 - 28 Feb 2001.
01-01-2001
LEE DA, Idowu BD,
Knight MM and Bader DL (2001).
Mechanical compression influences cytoskeletal oragnisation within chondrocytes seeded in agarose constructs. 47th Annual Meeting, Orthopaedic Research Society San Francisco, California 25 Feb 2001 - 28 Feb 2001.
01-01-20012000
![Relevant Publication](/common/publications/images/fav.png)
Roberts SR,
Knight MM,
Lee DA and Bader DL (2000).
Intracellular - CA2+ signalling in compressed chondrocyte agarose constructs. 01-12-2000
Knight MM, Van De Breevaart Bravenboer J, Bader DL and
Lee DA (2000).
Compression induced cell and nucleus deformation in chondrocyte-alginate constructs. 01-12-2000![Relevant Publication](/common/publications/images/fav.png)
Idowu BD,
Knight MM, Bader DL and
Lee DA (2000).
Confocal analysis of cytoskeletal organisation within isolated chondrocyte sub-populations cultured in agarose. Histochem J vol. 32 (3), 165-174.
01-03-2000![Relevant Publication](/common/publications/images/fav.png)
Roberts SR,
Knight MM,
Lee DA and Bader DL (2000).
Intracellular calcium signalling in compressed chondrocyte agarose constructs. 01-02-2000![Relevant Publication](/common/publications/images/fav.png)
Knight DP,
KNIGHT MM and Vollrath F (2000).
Beta transition and stress-induced phase separation in the spinning of spider dragline silk. International Journal of Biological Macromolecules vol. 27 (3), 205-210.
01-01-2000
Lee DA,
Knight MM, Bolton JF, Idowu BD, Kayser MV and Bader DL (2000).
Chondrocyte deformation within compressed agarose constructs at the cellular and sub-cellular levels. J Biomech vol. 33 (1), 81-95.
01-01-20001998
Hing K and
Knight M (1998).
Prize-winning peeks at the microscopic world. 01-12-1998
Lee DA, Noguchi T,
Knight MM, O'Donnell L, Bentley G and Bader DL (1998).
Response of chondrocyte subpopulations cultured within unloaded and loaded agarose. J Orthop Res vol. 16 (6), 726-733.
01-11-1998
Knight MM,
Lee DA and Bader DL (1998).
The influence of elaborated pericellular matrix on the deformation of isolated articular chondrocytes cultured in agarose. Biochim Biophys Acta vol. 1405 (1-3), 67-77.
21-10-1998
Knight MM, Ghori SA,
Lee DA and Bader DL (1998).
Measurement of the deformation of isolated chondrocytes in agarose subjected to cyclic compression. Med Eng Phys vol. 20 (9), 684-688.
01-01-1998